Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate

Base Information

Chemical Name:Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate
CAS No.:113118-79-9
Molecular Formula:C₁₄H₁₃NO₃
Molecular Weight:243.262
Hs Code.:
DSSTox Substance ID:DTXSID90597833
Mol file:113118-79-9.mol

Synonyms:113118-79-9;Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate;SCHEMBL7618299;DTXSID90597833;ZSQJOUBQOHGYOJ-UHFFFAOYSA-N;3-formyl-4-methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Suppliers and Price of Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:243.08954328
Heavy Atom Count:18
Complexity:381

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C=CN(C=C1C=O)C(=O)OC2=CC=CC=C2

Technology Process of Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate

There total 4 articles about Phenyl 3-formyl-4-methylpyridine-1(4H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-86-1
pyridine

: 113118-79-9
3-formyl-4-methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) CuI, methyl sulfide / 1.) THF, -23 deg C, 10 min, 2.) THF, from -23 deg C to RT, 40 min

2: 1.) POCl₃, 2.) KOAc / 1.) CH₂Cl₂, RT, 20 h, 2.) CH₂Cl₂, water, reflux, 20 min

With copper(l) iodide; dimethylsulfide; potassium acetate; trichlorophosphate;

Reference yield:

: 1885-14-9
phenyl chloroformate

: 113118-79-9
3-formyl-4-methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) CuI, methyl sulfide / 1.) THF, -23 deg C, 10 min, 2.) THF, from -23 deg C to RT, 40 min

2: 1.) POCl₃, 2.) KOAc / 1.) CH₂Cl₂, RT, 20 h, 2.) CH₂Cl₂, water, reflux, 20 min

With copper(l) iodide; dimethylsulfide; potassium acetate; trichlorophosphate;

Reference yield:

: 113118-87-9
4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 113118-79-9
3-formyl-4-methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: With potassium acetate; trichlorophosphate; Yield given. Multistep reaction; 1.) CH₂Cl₂, RT, 20 h, 2.) CH₂Cl₂, water, reflux, 20 min;