4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Base Information

Chemical Name:4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine
CAS No.:113118-87-9
Molecular Formula:C13H13NO2
Molecular Weight:215.252
Hs Code.:
DSSTox Substance ID:DTXSID301272257
Mol file:113118-87-9.mol

Synonyms:SCHEMBL7613473;AQHXCEMSAWOUNG-UHFFFAOYSA-N;DTXSID301272257;Phenyl 4-methyl-1(4H)-pyridinecarboxylate;4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine;113118-87-9

Suppliers and Price of 4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:215.094628657
Heavy Atom Count:16
Complexity:289

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C=CN(C=C1)C(=O)OC2=CC=CC=C2

Technology Process of 4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

There total 5 articles about 4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 110-86-1
pyridine

: 544-97-8
dimethyl zinc(II)

: 1885-14-9
phenyl chloroformate

: 113118-87-9
4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: pyridine; phenyl chloroformate; CuCN*2LiBr; In tetrahydrofuran; at 20 ℃;

dimethyl zinc(II); In tetrahydrofuran; at 20 ℃; for 1h; Further stages.;
DOI:10.1002/ejoc.200300387

Reference yield:

: 1336-21-6
ammonium hydroxide

: 676-58-4
methylmagnesium chloride

: 1885-14-9
phenyl chloroformate

: 113118-87-9
4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: With pyridine; dimethylsulfide; copper(I) iodide; In tetrahydrofuran;

Reference yield:

: 110-86-1
pyridine

: 113118-87-9
4-Methyl-1-(phenoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: copper(I) iodide / tetrahydrofuran / 0.08 h

2: copper(I) iodide

With copper(l) iodide; In tetrahydrofuran;
DOI:10.1021/jo970039v