1,4,7,10,13-Pentaoxacyclopentadecane

Base Information Edit

Chemical Name:1,4,7,10,13-Pentaoxacyclopentadecane
CAS No.:33100-27-5
Deprecated CAS:168081-57-0
Molecular Formula:C10H20O5
Molecular Weight:220.266
Hs Code.:2932.99
European Community (EC) Number:251-379-6
DSSTox Substance ID:DTXSID7067746
Nikkaji Number:J53.730F
Wikipedia:15-Crown-5
Wikidata:Q4550134
Metabolomics Workbench ID:54557
ChEMBL ID:CHEMBL156289
Mol file:33100-27-5.mol

Synonyms:15-crown-5

Suppliers and Price of 1,4,7,10,13-Pentaoxacyclopentadecane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
15-Crown-5 98+%
5g
$ 156.00

TRC
15-Crown-5
10g
$ 110.00

TCI Chemical
15-Crown 5-Ether >97.0%(GC)
25mL
$ 278.00

TCI Chemical
15-Crown 5-Ether >97.0%(GC)
5mL
$ 56.00

SynQuest Laboratories
15-Crown-5 98%
100 g
$ 146.00

SynQuest Laboratories
15-Crown-5 98%
5 g
$ 16.00

SynQuest Laboratories
15-Crown-5 98%
25 g
$ 40.00

Strem Chemicals
15-Crown-5, 98%
2g
$ 31.00

Strem Chemicals
15-Crown-5, 98%
10g
$ 128.00

Sigma-Aldrich
15-Crown-5 98%
25g
$ 186.00

Total 165 raw suppliers

Chemical Property of 1,4,7,10,13-Pentaoxacyclopentadecane Edit

Chemical Property:

Appearance/Colour:colourless liquid
Vapor Pressure:8.62E-05mmHg at 25°C
Melting Point:-20oC
Refractive Index:n20/D 1.465(lit.)
Boiling Point:350.9 °C at 760 mmHg
Flash Point:139.1 °C
PSA：46.15000
Density:0.995 g/cm³
LogP:0.08300
Storage Temp.:Store below +30°C.
Sensitive.:Hygroscopic
Solubility.:Miscible with organic solvents.
Water Solubility.:MISCIBLE
XLogP3:-0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:220.13107373
Heavy Atom Count:15
Complexity:86.2

Purity/Quality:

≥95.0% ^*data from raw suppliers

15-Crown-5 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 22-36/38-36-20/22-36/37/38-20/21/22
Safety Statements: 26-39-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Classes -> Other Organic Compounds
Canonical SMILES:C1COCCOCCOCCOCCO1
Uses 15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride, for performing reduction reactions in hydrocarbon solvents. Further, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.

Technology Process of 1,4,7,10,13-Pentaoxacyclopentadecane

There total 36 articles about 1,4,7,10,13-Pentaoxacyclopentadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 63689-58-7
1,4,7,10,13-pentaoxacyclopentadecane-2,6-dione

: 33100-27-5
15-crown-5

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1.5h;
DOI:10.1039/c39820000248

Reference yield: 75.0%

: 4792-15-8
Pentaethylene glycol

: 33100-27-5
15-crown-5

Guidance literature:: With sodium hydroxide; p-toluenesulfonyl chloride; In 1,4-dioxane; at 80 ℃;
DOI:10.1246/bcsj.53.1689

Reference yield: 70.2%

: 112-60-7
Tetraethylene glycol

: 107-21-1
ethylene glycol

: 33100-27-5
15-crown-5

Guidance literature:: With sodium carbonate; dicyclohexyl-carbodiimide; In 1,4-dioxane; at 70 - 75 ℃; for 6h; Concentration; Reagent/catalyst; Temperature; Solvent;