Ethyl 4-chloro-8-ethylquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 4-chloro-8-ethylquinoline-3-carboxylate
CAS No.:113515-72-3
Molecular Formula:C14H14ClNO2
Molecular Weight:263.724
Hs Code.:
DSSTox Substance ID:DTXSID60563247
Wikidata:Q82447632
Mol file:113515-72-3.mol

Synonyms:113515-72-3;Ethyl 4-chloro-8-ethylquinoline-3-carboxylate;4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester;3-Quinolinecarboxylic acid, 4-chloro-8-ethyl-, ethyl ester;SCHEMBL2021172;DTXSID60563247;WSVHEJIPUHPQMO-UHFFFAOYSA-N;MFCD11522694;AKOS000201381;4-Chloro-8-ethyl-quinoline-3-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 4-chloro-8-ethylquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Ethyl 4-chloro-8-ethylquinoline-3-carboxylate

Chemical Property:

Vapor Pressure:2.42E-05mmHg at 25°C
Boiling Point:359.2oC at 760 mmHg
Flash Point:171oC
PSA：39.19000
Density:1.221g/cm3
LogP:3.62730
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:263.0713064
Heavy Atom Count:18
Complexity:298

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C2C(=CC=C1)C(=C(C=N2)C(=O)OCC)Cl

Technology Process of Ethyl 4-chloro-8-ethylquinoline-3-carboxylate

There total 4 articles about Ethyl 4-chloro-8-ethylquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 59-31-4
2-hydroxyquinoline

: 144-55-8
sodium hydrogencarbonate

: 113515-72-3
ethyl 4-chloro-8-ethylquinoline-3-carboxylate

Guidance literature:: With trichlorophosphate; In ethyl acetate;

Reference yield:

: 71083-08-4,63136-14-1
MB₁_D_498479A-4

: 113515-72-3
ethyl 4-chloro-8-ethylquinoline-3-carboxylate

Guidance literature:: With trichlorophosphate;
DOI:10.1016/S0960-894X(03)00127-6

Reference yield:

: 578-54-1
ortho-ethylaniline

: 113515-72-3
ethyl 4-chloro-8-ethylquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 120 - 150 °C

1.2: Heating

2.1: POCl₃

With trichlorophosphate;
DOI:10.1016/S0960-894X(03)00127-6