Technology Process of 2-Pyrrolidinone,
3,4-dihydroxy-5-[(phenylmethoxy)methyl]-1-(phenylmethyl)-
There total 6 articles about 2-Pyrrolidinone,
3,4-dihydroxy-5-[(phenylmethoxy)methyl]-1-(phenylmethyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
osmium(VIII) oxide; 4-methylmorpholine N-oxide;
In
water; acetone;
for 14h;
Ambient temperature;
DOI:10.1248/cpb.38.2712
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaH / 1.) THF, DMF, RT, 1h, 2.) RT, 20h
2: 1.) lithium diisopropylamide / 1.) THF, hexane, -78 deg C, 40 min, 2.) THF, -78 deg C, 5 min
3: 81 percent / 30percent H2O2 / ethyl acetate / 0.5 h / 15 - 20 °C
4: 11 percent / OsO4, N-methylmorpholine N-oxide*H2O / acetone; H2O / 14 h / Ambient temperature
With
osmium(VIII) oxide; dihydrogen peroxide; sodium hydride; 4-methylmorpholine N-oxide; lithium diisopropyl amide;
In
water; ethyl acetate; acetone;
DOI:10.1248/cpb.38.2712
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaH / 1.) THF, DMF, RT, 1h, 2.) RT, 20h
2: 1.) lithium diisopropylamide / 1.) THF, hexane, -78 deg C, 40 min, 2.) THF, -78 deg C, 5 min
3: 81 percent / 30percent H2O2 / ethyl acetate / 0.5 h / 15 - 20 °C
4: 11 percent / OsO4, N-methylmorpholine N-oxide*H2O / acetone; H2O / 14 h / Ambient temperature
With
osmium(VIII) oxide; dihydrogen peroxide; sodium hydride; 4-methylmorpholine N-oxide; lithium diisopropyl amide;
In
water; ethyl acetate; acetone;
DOI:10.1248/cpb.38.2712
