n,n-Diethylpyridine-3-sulfonamide

Base Information

Chemical Name:n,n-Diethylpyridine-3-sulfonamide
CAS No.:4810-42-8
Molecular Formula:C9H14N2O2S
Molecular Weight:214.2847
Hs Code.:
NSC Number:25604
DSSTox Substance ID:DTXSID40282363
Nikkaji Number:J2.974.046A
Wikidata:Q82016618
Mol file:4810-42-8.mol

Synonyms:n,n-diethylpyridine-3-sulfonamide;4810-42-8;NSC25604;SCHEMBL2203883;DTXSID40282363;NSC-25604;FT-0751740

Suppliers and Price of n,n-Diethylpyridine-3-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of n,n-Diethylpyridine-3-sulfonamide

Chemical Property:

Vapor Pressure:0.00011mmHg at 25°C
Boiling Point:336.8°Cat760mmHg
Flash Point:157.5°C
Density:1.182g/cm³
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:214.07759887
Heavy Atom Count:14
Complexity:255

Purity/Quality:: 99%+, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)C1=CN=CC=C1

Technology Process of n,n-Diethylpyridine-3-sulfonamide

There total 5 articles about n,n-Diethylpyridine-3-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 16133-25-8
Pyridine-3-sulfonyl chloride

: 109-89-7
diethylamine

: 4810-42-8
N,N-diethylpyridine-3-sulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jacs.1c06481

Reference yield: 53.0%

: 16133-25-8
Pyridine-3-sulfonyl chloride

: 121-44-8
triethylamine

: 4810-42-8
N,N-diethylpyridine-3-sulfonamide

Guidance literature:: With copper(I) oxide; oxygen; In 1,2-dichloro-ethane; at 50 ℃; for 4h; under 760.051 Torr; Sealed tube;
DOI:10.1039/c6ob01208f

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 4810-42-8
N,N-diethylpyridine-3-sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 0.5 h / 20 °C

1.2: SO₂ / tetrahydrofuran / 0.5 h / -40 °C

1.3: SO₂Cl₂ / tetrahydrofuran / -40 - 20 °C

2.1: 460 mg / tetrahydrofuran / 3 h

With isopropylmagnesium chloride; In tetrahydrofuran;
DOI:10.1021/jo034643j