Benzamide, N-[[5-[4-[4-(3-chlorophenyl)-1-piperazinyl]-7-(trifluoromethyl)-3-quinolinyl ]-1,3,4-oxadiazol-2-yl]methyl]-

Base Information

Chemical Name:Benzamide, N-[[5-[4-[4-(3-chlorophenyl)-1-piperazinyl]-7-(trifluoromethyl)-3-quinolinyl ]-1,3,4-oxadiazol-2-yl]methyl]-
CAS No.:116247-40-6
Molecular Formula:C₃₀H₂₄ClF₃N₆O₂
Molecular Weight:593.008
Hs Code.:
Mol file:116247-40-6.mol

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, N-[[5-[4-[4-(3-chlorophenyl)-1-piperazinyl]-7-(trifluoromethyl)-3-quinolinyl ]-1,3,4-oxadiazol-2-yl]methyl]-

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Technology Process of Benzamide, N-[[5-[4-[4-(3-chlorophenyl)-1-piperazinyl]-7-(trifluoromethyl)-3-quinolinyl ]-1,3,4-oxadiazol-2-yl]methyl]-

There total 2 articles about Benzamide, N-[[5-[4-[4-(3-chlorophenyl)-1-piperazinyl]-7-(trifluoromethyl)-3-quinolinyl ]-1,3,4-oxadiazol-2-yl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 116270-43-0
N-[5-(4-Chloro-7-trifluoromethyl-quinolin-3-yl)-[1,3,4]oxadiazol-2-ylmethyl]-benzamide

: 6640-24-0
N-(m-chlorophenyl)piperazine

: 116247-40-6
N-(5-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-7-trifluoromethyl-quinolin-3-yl}-[1,3,4]oxadiazol-2-ylmethyl)-benzamide

Guidance literature:: With pyridine; In ethanol; for 8h; Heating;

Reference yield:

: 495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2
Hippuric Acid

: 116247-40-6
N-(5-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-7-trifluoromethyl-quinolin-3-yl}-[1,3,4]oxadiazol-2-ylmethyl)-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / POCl₃ / 10 h / Heating

2: 55 percent / pyridine / ethanol / 8 h / Heating

With pyridine; trichlorophosphate; In ethanol;