2,4-Dimethyloxazole

Base Information

• Chemical Name: 2,4-Dimethyloxazole
• CAS No.: 7208-05-1
• Molecular Formula: C5H7NO
• Molecular Weight: 97.1167
• Hs Code.: 2934999090
• European Community (EC) Number: 679-861-5
• UNII: G0W5QQT2LD
• DSSTox Substance ID: DTXSID60222408
• Nikkaji Number: J24.396E
• Wikidata: Q72471093
• Metabolomics Workbench ID: 45817
• Mol file: 7208-05-1.mol

Synonyms:2,4-Dimethyloxazole;7208-05-1;2,4-Dimethyl-1,3-oxazole;Oxazole, 2,4-dimethyl-;2,4-DIMETHYL-OXAZOLE;G0W5QQT2LD;dimethyl oxazole;2,4-dimethyl oxazole;UNII-G0W5QQT2LD;2,4-Dimethyl-1,3-oxazole #;DTXSID60222408;MFCD00234124;AKOS006280508;CS-W011337;D3766;FT-0654587;FT-0657045;EN300-102560;T71266;A837415

Chemical Property of 2,4-Dimethyloxazole

Chemical Property:

• Vapor Pressure: 30.9mmHg at 25°C
• Refractive Index: 1.449
• Boiling Point: 108 ºC at 760 mmHg
• PKA: 2.91±0.10(Predicted)
• Flash Point: 34.5 ºC
• PSA: 26.03000
• Density: 0.99 g/cm³
• LogP: 1.29140
• Storage Temp.: 2-8°C
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 97.052763847
• Heavy Atom Count: 7
• Complexity: 65.1

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dimethyloxazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=COC(=N1)C

Technology Process of 2,4-Dimethyloxazole

There total 2 articles about 2,4-Dimethyloxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cefalexin (15686-71-2,27726-35-8,34632-04-7,79814-91-8,108260-04-4) → 2,4-dimethyloxazole (7208-05-1) + N-(2-methylphenyl)acetamide (120-66-1) + 4-methoxy-N-pivaloylaniline (56619-94-4) + 1-(3-N-propoxyphenyl)-2-propane oxime

Guidance literature:

With dihydrogen peroxide; In water; at 60 ℃; pH=7; Reagent/catalyst; Wavelength; Concentration; pH-value; Temperature; Kinetics; Catalytic behavior; UV-irradiation;

DOI:10.1016/j.jphotochem.2017.02.003

Reference yield:

4-amino-3-penten-2-one (1118-66-7) + hydroxylamine (7803-49-8) → 2,4-dimethyloxazole (7208-05-1) + pentane-2,4-dione dioxime (2157-56-4)

Guidance literature:

Reference yield: 89.0%

2,4-dimethyloxazole (7208-05-1) + styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → 2,4-dimethyl-5-[(E)-styryl]oxazole (1236376-73-0)

Guidance literature:

With silver(I) acetate; palladium diacetate; propionic acid; at 120 ℃; for 8h; Inert atmosphere;

DOI:10.1021/jo101214y

upstream raw materials:

4-amino-3-penten-2-one

hydroxylamine

cefalexin

Downstream raw materials:

2-Styryl-4-methyloxazol

ethyl acetate

2,4-dimethylthiazole

2-methyl-3-ethoxycarbonyl-furan

Refernces