9-Hydroxy-2-nitrofluorene

Base Information

Chemical Name:9-Hydroxy-2-nitrofluorene
CAS No.:28149-15-7
Molecular Formula:C13H9 N O3
Molecular Weight:227.219
Hs Code.:
NSC Number:12398
DSSTox Substance ID:DTXSID701313831
Nikkaji Number:J619.860K
Wikidata:Q27105635
Metabolomics Workbench ID:68036
Mol file:28149-15-7.mol

Synonyms:2-Nitro-9H-fluoren-9-ol;9-Hydroxy-2-nitrofluorene;CCRIS 8021;9H-Fluoren-9-ol, 2-nitro-;28149-15-7;9-OHNF;2-nitro-fluorene-9-ol;CHEBI:2333;DTXSID701313831;NSC12398;NSC 12398;NSC-12398;LS-69300;Q27105635

Suppliers and Price of 9-Hydroxy-2-nitrofluorene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 9-Hydroxy-2-nitrofluorene

Chemical Property:

Vapor Pressure:2.16E-08mmHg at 25°C
Boiling Point:436.5°Cat760mmHg
Flash Point:190.7°C
Density:1.445g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:227.058243149
Heavy Atom Count:17
Complexity:314

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C3=C(C=C(C=C3)[N+](=O)[O-])C(C2=C1)O

Technology Process of 9-Hydroxy-2-nitrofluorene

There total 13 articles about 9-Hydroxy-2-nitrofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3096-52-4
2-nitro-9H-fluoren-9-one

: 28149-15-7
9-Hydroxy-2-nitrofluorene

Guidance literature:: With aluminum isopropoxide; In isopropyl alcohol; for 2h; Heating;
DOI:10.1016/S0165-1218(96)90022-1

Reference yield:

: 3096-52-4
2-nitro-9H-fluoren-9-one

: 33417-27-5
2-amino-9-hydroxyfluorene

: 28149-15-7
9-Hydroxy-2-nitrofluorene

: 3096-57-9
2-amino-9-fluorenone

Guidance literature:: With Tris-HCl buffer; 1,4-dihydronicotinamide adenine dinucleotide; DL-dithiothreitol; female Sprague-Dawley rat mammary gland cytosol; In dimethyl sulfoxide; at 37 ℃; pH=7.4; Enzyme kinetics;
DOI:10.1021/tx0000567

Reference yield:

: 98-80-6
phenylboronic acid

: 28149-15-7
9-Hydroxy-2-nitrofluorene

Guidance literature:: Multi-step reaction with 7 steps

1: 2.) 2 M aq. Na₂CO₃ / 1.) Pd(PPh₃)4 / 1.) EtOH, DME, 10 min, 2.) reflux, 20 h

2: 73 percent / NBS / benzoyl peroxide / CCl₄ / 36 h / Heating

3: AgNO₃ / dioxane; H₂O / 18 h / Ambient temperature

4: aq. KOH / dioxane / 20 h / Ambient temperature

5: 72 percent / aq. KMnO₄ / acetone / 4 h / Ambient temperature

6: 66 percent / polyphosphoric acid / 5 h / 160 °C

7: 64.5 percent / Et₃SiH / trifluoroacetic acid / 48 h / Ambient temperature

With triethylsilane; potassium hydroxide; potassium permanganate; N-Bromosuccinimide; PPA; sodium carbonate; silver nitrate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; dibenzoyl peroxide; In 1,4-dioxane; tetrachloromethane; water; acetone; trifluoroacetic acid;
DOI:10.1055/s-1989-27189