Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate

Base Information

Chemical Name:Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate
CAS No.:123705-52-2
Molecular Formula:C18H15NO3
Molecular Weight:293.322
Hs Code.:
DSSTox Substance ID:DTXSID60559125
Wikidata:Q82441706

Synonyms:123705-52-2;Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate;SCHEMBL8139729;DTXSID60559125

Suppliers and Price of Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:293.10519334
Heavy Atom Count:22
Complexity:361

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate

There total 3 articles about Methyl (4,5-diphenyl-1,3-oxazol-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 37517-81-0
3-chloro-3-oxopropanoic acid methyl ester

: 119-53-9,579-44-2
2-hydroxy-2-phenylacetophenone

: 123705-52-2
methyl 2-(4,5-diphenyloxazol-2-yl)acetate

Guidance literature:: With pyridine; dmap; In dichloromethane; at 0 - 20 ℃; for 3.5h;
DOI:10.1021/jo015617t

Reference yield: 44.0%

: 451-40-1
phenyl benzyl ketone

: 105-34-0
methyl 2-cyanoacetate

: 123705-52-2
methyl 2-(4,5-diphenyloxazol-2-yl)acetate

Guidance literature:: With potassium peroxymonosulfate sulfate; trifluorormethanesulfonic acid; iodine; at 70 ℃; for 6h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.1c00235