1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-

Base Information

Chemical Name:1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-
CAS No.:124443-67-0
Molecular Formula:C14H11FN2
Molecular Weight:226.253
Hs Code.:
Mol file:124443-67-0.mol

Synonyms:1-(4-fluorophenyl)methyl-1H-benzimidazole;1-(4-fluorobenzyl)-1H-benzo[d]imidazole;1-(4-fluorophenylmethyl)-1H-benzimidazole;

Suppliers and Price of 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-

Chemical Property:

PSA：17.82000
LogP:3.22370

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-

There total 6 articles about 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 459-57-4
4-fluorobenzaldehyde

: 95-54-5
1,2-diamino-benzene

: 124443-67-0
1-[(4-fluorophenyl)methyl]-1H-benzimidazole

Guidance literature:: With C₂₃H₃BF₁₆N₂O; In toluene; at 25 ℃; for 3h; Reagent/catalyst; Green chemistry;

Reference yield: 98.0%

: 51-17-2,79351-71-6
benzoimidazole

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 124443-67-0
1-[(4-fluorophenyl)methyl]-1H-benzimidazole

Guidance literature:: benzoimidazole; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;

1-chloromethyl-4-fluorobenzene; In tetrahydrofuran; at 0 - 65 ℃; for 14h; Inert atmosphere;
DOI:10.1002/ejoc.201101711

Reference yield: 97.0%

: 51-17-2,79351-71-6
benzoimidazole

: 459-46-1
4-Fluorobenzyl bromide

: 124443-67-0
1-[(4-fluorophenyl)methyl]-1H-benzimidazole

Guidance literature:: benzoimidazole; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.25h;

4-Fluorobenzyl bromide; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1039/d0ra00738b