N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide

Base Information

Chemical Name:N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide
CAS No.:124856-96-8
Molecular Formula:C18H18BrNO3
Molecular Weight:376.25
Hs Code.:
DSSTox Substance ID:DTXSID30562767
Nikkaji Number:J306.213I
Mol file:124856-96-8.mol

Synonyms:124856-96-8;N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide;DTXSID30562767

Suppliers and Price of N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:375.04701
Heavy Atom Count:23
Complexity:409

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=CC=C1C(=O)C(C(C2=CC=CC=C2)OC)Br

Technology Process of N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide

There total 5 articles about N-[2-(2-Bromo-3-methoxy-3-phenylpropanoyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 67-56-1
methanol

: 131423-38-6
[E]-3-phenyl-1-(2-acetamidophenyl)prop-2-en-1-one

: 124856-96-8
1-(2-Acetamidophenyl)-2-bromo-3-methoxy-3-phenyl-1-propanone

Guidance literature:: With N-butylbenzenesulfonamide; In methanol; for 3h;
DOI:10.1021/jo00293a017

Reference yield:

: 78396-00-6
2-aminochalcone

: 124856-96-8
1-(2-Acetamidophenyl)-2-bromo-3-methoxy-3-phenyl-1-propanone

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / pyridine

2: 60 percent / NBBS / methanol / 3 h

With pyridine; N-butylbenzenesulfonamide; In methanol;
DOI:10.1021/jo00293a017

Reference yield:

: 551-93-9
2-aminoacetophenone

: 124856-96-8
1-(2-Acetamidophenyl)-2-bromo-3-methoxy-3-phenyl-1-propanone

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / ethanol. NaOH / 8 h / 5 °C

2: 72 percent / pyridine

3: 60 percent / NBBS / methanol / 3 h

With pyridine; sodium hydroxide; N-butylbenzenesulfonamide; In methanol;
DOI:10.1021/jo00293a017