Boronic acid, [2-[(diethylamino)carbonyl]-3-methoxyphenyl]-

Base Information

Chemical Name:Boronic acid, [2-[(diethylamino)carbonyl]-3-methoxyphenyl]-
CAS No.:133730-22-0
Molecular Formula:C12H18BNO4
Molecular Weight:251.08700
Hs Code.:

Synonyms:.(3-Methoxy-2-(diethylcarbamoyl)phenyl)boronic acid;2-N,N-diethylcarboxamido-3-methoxyphenyl boronic acid;.[3-Methoxy-2-(diethylcarbamoyl)phenyl]boronic acid;

Suppliers and Price of Boronic acid, [2-[(diethylamino)carbonyl]-3-methoxyphenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Boronic acid, [2-[(diethylamino)carbonyl]-3-methoxyphenyl]-

Chemical Property:

Boiling Point:479.0±55.0 °C(Predicted)
PSA：70.00000
Density:1.16±0.1 g/cm3(Predicted)
LogP:-0.14300

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Boronic acid, [2-[(diethylamino)carbonyl]-3-methoxyphenyl]-

There total 4 articles about Boronic acid, [2-[(diethylamino)carbonyl]-3-methoxyphenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 51674-10-3
N,N-diethyl-2-methoxybenzamide

: 133730-22-0
3-methoxy-2-(N,N-diethylcarboxamido)phenylboronic acid

Guidance literature:: N,N-diethyl-2-methoxybenzamide; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 1h;

Trimethyl borate; In tetrahydrofuran; cyclohexane; at -78 - 20 ℃;

With hydrogenchloride; ammonium chloride; In tetrahydrofuran; cyclohexane; pH=5 - 6;
DOI:10.1139/v00-055

Reference yield:

: 51674-10-3
N,N-diethyl-2-methoxybenzamide

: 133730-22-0
3-methoxy-2-(N,N-diethylcarboxamido)phenylboronic acid

Guidance literature:: N,N-diethyl-2-methoxybenzamide; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; hexane; at -78 - -70 ℃; for 1.25h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; hexane; at -78 - -40 ℃; Inert atmosphere;
DOI:10.1002/chem.201000401

Reference yield:

: 5419-55-6
Triisopropyl borate

: 51674-10-3
N,N-diethyl-2-methoxybenzamide

: 133730-22-0
3-methoxy-2-(N,N-diethylcarboxamido)phenylboronic acid

Guidance literature:: N,N-diethyl-2-methoxybenzamide; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -70 ℃; for 1h;

Triisopropyl borate; In tetrahydrofuran; cyclohexane; at -70 - 20 ℃;
DOI:10.1021/acs.joc.5b01300