4-(2-Pyridyl)benzaldehyde

Base Information

Chemical Name:4-(2-Pyridyl)benzaldehyde
CAS No.:127406-56-8
Molecular Formula:C12H9NO
Molecular Weight:183.21
Hs Code.:29333990
European Community (EC) Number:627-948-3
UNII:65SW8X25MX
DSSTox Substance ID:DTXSID90363914
Nikkaji Number:J915.868E
Wikidata:Q72504075
ChEMBL ID:CHEMBL3542349
Mol file:127406-56-8.mol

Synonyms:4-pyridin-2-ylbenzaldehyde

Suppliers and Price of 4-(2-Pyridyl)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-Pyridinyl)benzaldehyde
10g
$ 235.00

TRC
4-(2-Pyridinyl)benzaldehyde
2.5g
$ 90.00

TCI Chemical
4-(2-Pyridyl)benzaldehyde >95.0%(GC)(T)
5g
$ 32.00

TCI Chemical
4-(2-Pyridyl)benzaldehyde >95.0%(GC)(T)
1g
$ 12.00

SynQuest Laboratories
4-(Pyridin-2-yl)benzaldehyde
1 g
$ 16.00

SynChem
4-Pyridin-2-yl-benzaldehyde 95+%
100 g
$ 420.00

SynChem
4-Pyridin-2-yl-benzaldehyde 95+%
5 g
$ 35.00

SynChem
4-Pyridin-2-yl-benzaldehyde 95+%
10 g
$ 60.00

Sigma-Aldrich
4-(2-Pyridyl)benzaldehyde 97%
5g
$ 51.00

Sigma-Aldrich
4-(2-Pyridyl)benzaldehyde 99%
5g
$ 51.00

Total 133 raw suppliers

Chemical Property of 4-(2-Pyridyl)benzaldehyde

Chemical Property:

Appearance/Colour:acicular white solid
Vapor Pressure:8.62E-05mmHg at 25°C
Melting Point:51-53 ºC
Refractive Index:1.614
Boiling Point:340.4 ºC at 760 mmHg
PKA:3.97±0.25(Predicted)
Flash Point:167.6 ºC
PSA：29.96000
Density:1.147 g/cm³
LogP:2.56110
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Soluble in Chloroform
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:183.068413911
Heavy Atom Count:14
Complexity:185

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Pyridinyl)benzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 26-36/37-36/37/39-22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)C2=CC=C(C=C2)C=O
Uses Reactive metabolite of atazanavir. Reactive metabolite of atazanavir. Atazanavir Impurity; Pyridinyl Benzaldehyde impurity

Technology Process of 4-(2-Pyridyl)benzaldehyde

There total 28 articles about 4-(2-Pyridyl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 109-04-6
2-bromo-pyridine

: 87199-17-5
4-formylphenylboronic acid,

: 127406-56-8
4-(2'-pyridyl)benzaldehyde

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; for 8h; Reflux;
DOI:10.1002/ejoc.200701200

Reference yield: 100.0%

: 109-04-6
2-bromo-pyridine

: 24856-58-4
1,1-dimethoxy-1-(4-bromophenyl)methane

: 127406-56-8
4-(2'-pyridyl)benzaldehyde

Guidance literature:: 1,1-dimethoxy-1-(4-bromophenyl)methane; With iodine; magnesium; In tetrahydrofuran; at 30 - 35 ℃; for 2h;

2-bromo-pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; zinc(II) chloride; In tetrahydrofuran; toluene; at 50 ℃; for 2.5h;

With hydrogenchloride; ammonia; water; more than 3 stages; Conversion of starting material;

Reference yield: 100.0%

: 109-09-1
2-chloropyridine

: 24856-58-4
1,1-dimethoxy-1-(4-bromophenyl)methane

: 127406-56-8
4-(2'-pyridyl)benzaldehyde

Guidance literature:: 1,1-dimethoxy-1-(4-bromophenyl)methane; With iodine; magnesium; In tetrahydrofuran; at 30 - 35 ℃; for 2.5h;

2-chloropyridine; With 1,4-di(diphenylphosphino)-butane; palladium diacetate; zinc(II) chloride; In tetrahydrofuran; at 70 ℃; for 3.5h; Conversion of starting material;