3,5-Bis(methoxymethyl)benzaldehyde

Base Information

Chemical Name:3,5-Bis(methoxymethyl)benzaldehyde
CAS No.:137334-70-4
Molecular Formula:C11H14O3
Molecular Weight:194.23
Hs Code.:
DSSTox Substance ID:DTXSID50568781
Nikkaji Number:J2.090.190J
Wikidata:Q82455138

Synonyms:3,5-bis(methoxymethyl)benzaldehyde;137334-70-4;SCHEMBL3605246;DTXSID50568781;KJLBECPMEXYTQS-UHFFFAOYSA-N

Suppliers and Price of 3,5-Bis(methoxymethyl)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3,5-Bis(methoxymethyl)benzaldehyde

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:194.094294304
Heavy Atom Count:14
Complexity:156

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCC1=CC(=CC(=C1)C=O)COC

Technology Process of 3,5-Bis(methoxymethyl)benzaldehyde

There total 4 articles about 3,5-Bis(methoxymethyl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 107146-47-4
3,5-bis(methoxymethyl)iodobenzene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 137334-70-4
3,5-bis(methoxymethyl)benzaldehyde

Guidance literature:: 3,5-bis(methoxymethyl)iodobenzene; With tert.-butyl lithium; In diethyl ether; pentane; at -78 ℃; for 0.5h;

N,N-dimethyl-formamide; In diethyl ether; pentane; at -78 - 20 ℃;
DOI:10.1021/ol049034s

Reference yield: 59.0%

: 627-41-8
propargyl alcohol methyl ether

: 84941-01-5
1,3,5-tris(methoxymethyl)benzene

: 84941-00-4
1,2,4-tris(methoxymethyl)-benzene

: 137334-70-4
3,5-bis(methoxymethyl)benzaldehyde

Guidance literature:: With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; 2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; hydrogen; In dichloromethane; at 20 ℃; for 3h; Schlenk technique;
DOI:10.1002/anie.201903422

Reference yield:

: 4394-85-8
4-morpholinecarboxaldehyde

: 137334-69-1
1-bromo-3,5-bis(methoxymethyl)benzene

: 137334-70-4
3,5-bis(methoxymethyl)benzaldehyde

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexanes, -78 deg C, 2 min, 2.) to 25 deg C;
DOI:10.1021/jo00027a011