4,6-Dimethylpyridine-2-carbaldehyde

Base Information

• Chemical Name: 4,6-Dimethylpyridine-2-carbaldehyde
• CAS No.: 5439-01-0
• Molecular Formula: C8H9NO
• Molecular Weight: 135.166
• NSC Number: 15045
• DSSTox Substance ID: DTXSID20279993
• Wikidata: Q82012990
• Mol file: 5439-01-0.mol

Synonyms:4,6-dimethylpyridine-2-carbaldehyde;5439-01-0;4,6-Dimethylpicolinaldehyde;NSC15045;4,6-dimethyl-pyridine-2-carbaldehyde;SCHEMBL1646533;DTXSID20279993;4,6-Dimethyl pyridine-2-aldehyde;NSC 15045;NSC-15045;AKOS006271603;AB04218;4,6-DIMETHYL-2-PYRIDINECARBALDEHYDE;CS-0437069;EN300-112493;Z1198151514

Chemical Property of 4,6-Dimethylpyridine-2-carbaldehyde

Chemical Property:

• Vapor Pressure: 0.14mmHg at 25°C
• Boiling Point: 216.4°C at 760 mmHg
• Flash Point: 89.4°C
• Density: 1.065g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 135.068413911
• Heavy Atom Count: 10
• Complexity: 124

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NC(=C1)C=O)C

Technology Process of 4,6-Dimethylpyridine-2-carbaldehyde

There total 8 articles about 4,6-Dimethylpyridine-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4,6-dimethylpyridine-2-carboxylic acid methoxymethylamide → 4,6-dimethylpyridine-2-carbaldehyde (5439-01-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

Reference yield: 51.0%

4,6-dimethyl-2-(hydroxymethyl)pyridine (18087-99-5) → 4,6-dimethylpyridine-2-carbaldehyde (5439-01-0)

Guidance literature:

With manganese(IV) oxide; In chloroform; Heating / reflux;

Reference yield:

2,4,6-trimethyl-pyridine (108-75-8) → 4,6-dimethylpyridine-2-carbaldehyde (5439-01-0) + 2,6-dimethyl-4-pyridine carboxaldehyde (18206-06-9)

Guidance literature:

β-VO(PO3)2; In gas; at 400 ℃; Product distribution; Rate constant; selectivity of reaction, rates of partial and total oxidation;

DOI:10.1007/BF00515425

upstream raw materials:

2,4,6-trimethyl-pyridine

4,6-dimethylpyridine-2-carbonitrile

4,6-dimethyl-2-(hydroxymethyl)pyridine

4,6-dimethylpyridine-2-carboxylic acid

Downstream raw materials:

4,6-dimethylpyridine-2-carboxylic acid

Methyl-4,6-dimethyl-2-pyridincarboxylat

(4,6-dimethylpyridin-2-ylmethyl)(4-nitrophenyl)amine