4-HYDROXYMIDAZOLAM

Base Information

Chemical Name:4-HYDROXYMIDAZOLAM
CAS No.:59468-85-8
Molecular Formula:C18H13 Cl F N3 O
Molecular Weight:341.772
Hs Code.:
UNII:LIW2RH792R
DSSTox Substance ID:DTXSID20974870
Nikkaji Number:J344.584D
ChEMBL ID:CHEMBL2074876
Mol file:59468-85-8.mol

Synonyms:4-Hydroxymidazolam

Suppliers and Price of 4-HYDROXYMIDAZOLAM

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-Hydroxymidazolam
5mg
$ 1180.00

American Custom Chemicals Corporation
4-HYDROXY MIDAZOLAM 95.00%
50MG
$ 1732.50

American Custom Chemicals Corporation
4-HYDROXY MIDAZOLAM 95.00%
5MG
$ 756.25

Total 12 raw suppliers

Chemical Property of 4-HYDROXYMIDAZOLAM

Chemical Property:

Vapor Pressure:5.9E-13mmHg at 25°C
Melting Point:186-187 °C
Boiling Point:550.6°C at 760 mmHg
PKA:12.69±0.40(Predicted)
Flash Point:286.8°C
PSA：50.41000
Density:1.44g/cm³
LogP:3.25070
Storage Temp.:2-8°C
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:341.0731179
Heavy Atom Count:24
Complexity:505

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Hydroxymidazolam ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2O)C4=CC=CC=C4F
Uses A metabolite of Midazolam (M343000). 4′-Hydroxymidazolam can be used in cell biology studies. It can also be used for studying cell signaling and neuroscience.

Technology Process of 4-HYDROXYMIDAZOLAM

There total 8 articles about 4-HYDROXYMIDAZOLAM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59468-84-7
4-acetoxymidazolam

: 59468-85-8
4-hydroxymidazolam

Guidance literature:: With sodium hydroxide; In methanol; at 0 - 10 ℃;

Reference yield:

: 59467-70-8
Midazolam

: 81256-81-7
1-hydroxymethylmidazolam glucuronide

: 4-hydroxymethylmidazolam glucuronide

: 64740-68-7
1',4-Dihydroxymidazolam

: 59468-85-8
4-hydroxymidazolam

Guidance literature:: metabolism (female dogs, 2-5 mg/kg, i.v.; human, 10 mg/kg, i.v.);

Reference yield:

: 59468-83-6
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-oxide

: 59468-85-8
4-hydroxymidazolam

Guidance literature:: Multi-step reaction with 2 steps

1: 95 - 105 °C

2: sodium hydroxide / methanol / 0 - 10 °C

With sodium hydroxide; In methanol;