1,4-Dioxaspiro[4.5]decan-8-yl methanesulfonate

Base Information

• Chemical Name: 1,4-Dioxaspiro[4.5]decan-8-yl methanesulfonate
• CAS No.: 141120-33-4
• Molecular Formula: C9H16O5S
• Molecular Weight: 236.289
• Hs Code.: 2932999099
• European Community (EC) Number: 967-670-2
• DSSTox Substance ID: DTXSID60566197
• Wikidata: Q82451691
• Mol file: 141120-33-4.mol

Synonyms:141120-33-4;1,4-dioxaspiro[4.5]decan-8-yl methanesulfonate;1,4-Dioxa-spiro[4.5]dec-8-yl methanesulfonate;MFCD09953114;methanesulfonic acid 1,4-dioxaspiro[4.5]decan-8-yl ester;AB3686;SCHEMBL101485;C9H16O5S;DTXSID60566197;XSLHQJJTBVYMJX-UHFFFAOYSA-N;AKOS015996053;AS-44727;CS-0208021;1,4-Dioxa-spiro[4.5]dec-8-ylmethanesulfonate;1,4-Dioxaspiro[4,5]dec-8-yl methanesulfonate;1,4-dioxaspiro[4.5]dec-8-yl methanesulfonate;8-methylsulfonyloxy-1,4-dioxaspiro[4.5]decane;1,4-dioxa-spiro[4.5]dec-8-yl methanesulphonate;8-methanesulphonyloxy-1,4-dioxa-spiro[4,5]decane;8-methanesulphonyloxy-1,4-dioxa-spiro[4.5]decan;A807732;methanesulfonic acid 1,4-dioxa-spiro[4.5]dec-8-yl ester

Chemical Property of 1,4-Dioxaspiro[4.5]decan-8-yl methanesulfonate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.509
• Boiling Point: 398.624°C at 760 mmHg
• Flash Point: 194.881°C
• PSA: 70.21000
• Density: 1.315g/cm³
• LogP: 1.72910
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 236.07184478
• Heavy Atom Count: 15
• Complexity: 302

Purity/Quality:

97% ^*data from raw suppliers

1,4-Dioxaspiro[4.5]decan-8-ylMethanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)OC1CCC2(CC1)OCCO2

Technology Process of 1,4-Dioxaspiro[4.5]decan-8-yl methanesulfonate

There total 5 articles about 1,4-Dioxaspiro[4.5]decan-8-yl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,4-ethylenedioxycyclohexan-1-ol (22428-87-1) + methanesulfonyl chloride (124-63-0) → 8-methylsulfonyloxy-1,4-dioxaspiro[4.5]decane (141120-33-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield: 90.0%

→ 8-methylsulfonyloxy-1,4-dioxaspiro[4.5]decane (141120-33-4)

Guidance literature:

Reference yield: 89.0%

cyclohexanedione monoethylene ketal (4746-97-8) + methane sulfonyl chloride → 8-methylsulfonyloxy-1,4-dioxaspiro[4.5]decane (141120-33-4)

Guidance literature:

With sodium borohydrid; triethylamine; In ethanol; dichloromethane; water; acetic acid; ethyl acetate;

upstream raw materials:

4,4-ethylenedioxycyclohexan-1-ol

methanesulfonyl chloride

cyclohexanedione monoethylene ketal

1,4-dioxaspiro[4,5]decan-9-ol

Downstream raw materials:

1,4-dioxaspiro<4.5>dec-7-ene

8-(4-chlorobenzylthio)-1,4-dioxaspiro[4.5]decane

4-(4-chlorobenzylthio)cyclohexanone

1-(4-chlorobenzylthio)-4-(methoxymethylene)cyclohexane