Maytansinol-3-propionate

Base Information

Chemical Name:Maytansinol-3-propionate
CAS No.:57103-70-5
Molecular Formula:C31H41 Cl N2 O9
Molecular Weight:621.12
Hs Code.:
Wikidata:Q77561337
Metabolomics Workbench ID:104355
ChEMBL ID:CHEMBL3245319

Synonyms:Ansamitocin P 2;Maytansinol-3-propionate;Maytansinol propionate;Maytansine, 2'-de(acetylmethylamino)-;57103-70-5;C31-H41-Cl-N2-O9;ansamitocin P-2;Ansamitocin-P-2;CHEMBL3245319;SCHEMBL15705857;DGBBXVWXOHSLTG-UMDRASRXSA-N

Suppliers and Price of Maytansinol-3-propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Maytansinol-3-propionate

Chemical Property:

Vapor Pressure:2.23E-29mmHg at 25°C
Boiling Point:832.4°Cat760mmHg
Flash Point:457.2°C
PSA：139.65000
Density:1.31g/cm³
LogP:3.78260
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:620.2500586
Heavy Atom Count:43
Complexity:1120

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)OC1CC(=O)N(C2=C(C(=CC(=C2)CC(=CC=CC(C3(CC(C(C4C1(O4)C)C)OC(=O)N3)O)OC)C)OC)Cl)C
Isomeric SMILES:CCC(=O)O[C@H]1CC(=O)N(C2=C(C(=CC(=C2)C/C(=C/C=C/[C@H]([C@]3(C[C@@H]([C@H]([C@H]4[C@]1(O4)C)C)OC(=O)N3)O)OC)/C)OC)Cl)C

Technology Process of Maytansinol-3-propionate

There total 3 articles about Maytansinol-3-propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38997-10-3,70774-06-0
maytanbutine

: 57103-70-5
C-15003 P-2,Maytanacinolpropionat

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / 3 h / -23 °C

2: Py / 72 h / 45 °C

With pyridine; lithium aluminium tetrahydride; In tetrahydrofuran;
DOI:10.1021/jm00199a006