5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide

Base Information

Chemical Name:5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide
CAS No.:142885-92-5
Molecular Formula:C17H19N3O3S
Molecular Weight:345.422
Hs Code.:
Mol file:142885-92-5.mol

Synonyms:5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide;

Suppliers and Price of 5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazoleN-Oxide
100mg
$ 1190.00

Medical Isotopes, Inc.
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazoleN-Oxide
5 mg
$ 650.00

Total 12 raw suppliers

Chemical Property of 5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide

Chemical Property:

Melting Point:186-188 °C
Boiling Point:632.6±65.0 °C(Predicted)
PKA:9.42±0.10(Predicted)
PSA：97.90000
Density:1.31±0.1 g/cm3(Predicted)
LogP:3.91770
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Sl

Purity/Quality:

NLT 98% ^*data from raw suppliers

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazoleN-Oxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide is a metabolite of Omeprazole (O635000), an proton inhibitor used as an antiulcerative agent.

Technology Process of 5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide

There total 3 articles about 5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 142885-90-3
5-METHOXY-2-((3,5-DIMETHYL-4-NITRO-2-PYRIDINYL-N-OXIDE)-METHYLTHIO)-1H-BENZIMIDAZOLE

: 75-09-2
dichloromethane

: 142885-92-5
5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzimidazole

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; sodium methylate; In methanol; water;

Reference yield: 88.0%

: 848694-10-0
2-chloromethyl-3,5-dimethyl-4-methoxypyridine-N-oxide

: 37052-78-1
2-Mercapto-5-methoxybenzimidazole

: 142885-92-5
5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzimidazole

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1080/00397910701470693

Reference yield:

: 86604-75-3
2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine hydrochloride

: 142885-92-5
5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium bicarbonate / CHCl₃

1.2: 52.47 percent / m-chloroperbenzoic acid / 2.42 h / 5 °C

2.1: 88 percent / potassium carbonate / dimethylformamide / 20 °C

With sodium hydrogencarbonate; potassium carbonate; In chloroform; N,N-dimethyl-formamide;
DOI:10.1080/00397910701470693