1,1,2,2-Tetraethoxyethane

Base Information

• Chemical Name: 1,1,2,2-Tetraethoxyethane
• CAS No.: 3975-14-2
• Molecular Formula: C10H22 O4
• Molecular Weight: 206.282
• European Community (EC) Number: 223-606-9
• NSC Number: 21541
• UNII: Y75ZE97UDA
• DSSTox Substance ID: DTXSID00192833
• Nikkaji Number: J35.929G
• Wikidata: Q83065499
• Mol file: 3975-14-2.mol

Synonyms:1,1,2,2-Tetraethoxyethane;3975-14-2;Ethane, 1,1,2,2-tetraethoxy-;EINECS 223-606-9;NSC-21541;1,1,2,2-tetraethoxy-ethane;NSC21541;Y75ZE97UDA;Ethane,1,2,2-tetraethoxy-;SCHEMBL1568155;DTXSID00192833;NSC 21541;A824724

Chemical Property of 1,1,2,2-Tetraethoxyethane

Chemical Property:

• Vapor Pressure: 0.0591mmHg at 25°C
• Boiling Point: 240.3°Cat760mmHg
• Flash Point: 67.5°C
• PSA: 36.92000
• Density: 0.938g/cm³
• LogP: 1.78460
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 206.15180918
• Heavy Atom Count: 14
• Complexity: 92.7

Purity/Quality:

95-99% ^*data from raw suppliers

1,1,2,2-TETRAETHOXYETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(C(OCC)OCC)OCC
• Uses: 1,1,2,2-Tetraethoxyethane is a low-toxicity preservative that can be used for human and animal corpses.

Technology Process of 1,1,2,2-Tetraethoxyethane

There total 12 articles about 1,1,2,2-Tetraethoxyethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethanol (64-17-5) + Glyoxal (131543-46-9,107-22-2) → 1,1,2,2-tetraethoxyethane (3975-14-2)

Guidance literature:

With zirconium sulphate; magnesium sulfate; In chloroform; water; for 10h; Heating;

Reference yield: 67.0%

ethanol (64-17-5) + Glyoxal (131543-46-9,107-22-2) → 1,1,2,2-tetraethoxyethane (3975-14-2) + diethoxyacetaldehyde (5344-23-0)

Guidance literature:

With zirconium sulphate; magnesium sulfate; In chloroform; for 2.5h; Product distribution; Heating; further reagents, time;

Reference yield:

dichloroacetaldehyde diethyl acetal (619-33-0) → 1,1,2,2-tetraethoxyethane (3975-14-2)

Guidance literature:

With sodium ethanolate;

upstream raw materials:

2,3-dichloro-1,4-dioxane

ethanol

dichloroacetaldehyde diethyl acetal

sodium ethanolate

Downstream raw materials:

1,2-diethoxy-1,2-diphenylethane

tetraethyl 4,5-bis(4-methoxyphenyl)cyclohex-4-ene-1,1,2,2-tetracarboxylate

glycoaldehyde diethyl acetal

Maleinaldehydsaeure-ethylester-diethylacetal

Refernces

• 1、 -. "Process for continuously preparing acetals of alpha, beta-dicarbonyl compounds". Page 3. . Retrieved 2008/06/13.
• 2、 Stambouli, Abdelhamid,Hamedi-Sangsari, Farid,Amouroux, Roger,Chastrette, Francine,Blanc, Alain,Mattioda, Georges. "Les dialkoxy-2,2 ethanals, synthons difonctionnels a deux carbones : preparation par acetalisation du glyoxal et quelques applications en synthese". . p. 95 - 100. Retrieved 2007/10/02.