2,2-diethoxyacetaldehyde

Base Information

• Chemical Name: 2,2-diethoxyacetaldehyde
• CAS No.: 5344-23-0
• Molecular Formula: C6H12O3
• Molecular Weight: 132.159
• Hs Code.: 2912499000
• Mol file: 5344-23-0.mol

Synonyms:2,2-diethoxy acetaldehyde;2,2-diethoxy-heptan-3-one;glyoxal mono-(diethyl acetal);Glyoxal-mono-diaethylacetal;diethoxy-2,2 heptanone-3;diethoxyacetaldehyde;2,2-diethoxyetanal;diethoxyethanal;3-Heptanone,2,2-diethoxy;

Chemical Property of 2,2-diethoxyacetaldehyde

Chemical Property:

• Vapor Pressure: 15.5mmHg at 25°C
• Boiling Point: 120°Cat760mmHg
• Flash Point: 16°C
• PSA: 35.53000
• Density: 0.957g/cm³
• LogP: 0.58440

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-diethoxyacetaldehyde

There total 15 articles about 2,2-diethoxyacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

acrylaldehyde diethyl acetal (3054-95-3) → diethoxyacetaldehyde (5344-23-0)

Guidance literature:

With dimethylsulfide; ozone; In ethanol; for 12h; 1.) -78 deg C, 2.) room temp.;

DOI:10.1055/s-1981-29360

Reference yield: 67.0%

ethanol (64-17-5) + Glyoxal (131543-46-9,107-22-2) → 1,1,2,2-tetraethoxyethane (3975-14-2) + diethoxyacetaldehyde (5344-23-0)

Guidance literature:

With zirconium sulphate; magnesium sulfate; In chloroform; for 2.5h; Product distribution; Heating; further reagents, time;

Reference yield:

3,3-diethoxypropane-1,2-diol (10487-05-5) → diethoxyacetaldehyde (5344-23-0)

Guidance literature:

durch Oxydation;

upstream raw materials:

pyridine

1,1,2-triethoxyethane

acrylaldehyde diethyl acetal

3,3-diethoxypropane-1,2-diol

Downstream raw materials:

2,3-dihydro-3-oxopyridazine-4-carbonitrile

m-tolylimino-acetaldehyde diethylacetal

(E)-1,1-Diethoxy-hex-2-ene

(2Z)-hexenal diethyl acetal

Refernces

Enantioselective synthesis of 2-isocephem and 2-isooxacephem antibiotics

10.1039/a700650k

The research focuses on the enantioselective synthesis of 2-isocephem and 2-isooxacephem antibiotics, which are nuclear analogues of β-lactam antibiotics and have shown potent antibacterial activity. The purpose of the study was to develop a method for synthesizing enantiomerically pure forms of these compounds, addressing the challenge of constructing cis-oriented chiral centers at the azetidinone ring. The researchers used L-aspartic acid as a chiral starting material and successfully synthesized the target compounds through a series of chemical reactions involving azide introduction, four-component condensation, and intramolecular acylation. Key chemicals used in the process included azido lactone, p-nitrobenzyl isocyanide, formaldehyde, 2,2-diethoxyacetaldehyde, and various protecting and deprotecting agents.