Imidazo(1,2-b)pyridazine, 2-phenyl-

Base Information

Chemical Name:Imidazo(1,2-b)pyridazine, 2-phenyl-
CAS No.:1844-54-8
Molecular Formula:C12H9N3
Molecular Weight:195.224
Hs Code.:
DSSTox Substance ID:DTXSID20171569
Wikidata:Q83041650
Mol file:1844-54-8.mol

Synonyms:2-phenylimidazo[1,2-b]pyridazine;1844-54-8;Imidazo(1,2-b)pyridazine, 2-phenyl-;Imidazo[1,2-b]pyridazine,2-phenyl-;SCHEMBL1202800;DTXSID20171569;MFCD29068773

Suppliers and Price of Imidazo(1,2-b)pyridazine, 2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Imidazo(1,2-b)pyridazine, 2-phenyl-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.21g/cm³
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:195.079647300
Heavy Atom Count:15
Complexity:213

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CN3C(=N2)C=CC=N3

Technology Process of Imidazo(1,2-b)pyridazine, 2-phenyl-

There total 4 articles about Imidazo(1,2-b)pyridazine, 2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 5469-70-5
3-aminopyridazine

: 2,2-dimethoxy-2-phenylethyl 4-methylbenzenesulfonate

: 1844-54-8
2-phenylimidazo<1,2-b>pyridazine

Guidance literature:: With scandium tris(trifluoromethanesulfonate); In acetonitrile; at 140 ℃; for 12h;
DOI:10.1021/acs.orglett.5b02966

Reference yield: 40.0%

: 5469-70-5
3-aminopyridazine

: 70-11-1
α-bromoacetophenone

: 1844-54-8
2-phenylimidazo<1,2-b>pyridazine

Guidance literature:: With sodium hydrogencarbonate; In ethanol; for 12h; Reflux;

Reference yield:

: 98-86-2
acetophenone

: 1844-54-8
2-phenylimidazo<1,2-b>pyridazine

Guidance literature:: Multi-step reaction with 3 steps

1: acetonitrile / 2 h / Reflux

2: toluene-4-sulfonic acid / methanol / 18 h / Reflux

3: scandium tris(trifluoromethanesulfonate) / acetonitrile / 12 h / 140 °C

With toluene-4-sulfonic acid; scandium tris(trifluoromethanesulfonate); In methanol; acetonitrile;
DOI:10.1021/acs.orglett.5b02966