OlMesartan interMediate iMpurity II

Base Information

Chemical Name:OlMesartan interMediate iMpurity II
CAS No.:144690-07-3
Molecular Formula:C11H16N2O3
Molecular Weight:224.26
Hs Code.:
Mol file:144690-07-3.mol

Synonyms:ethyl 4-acetyl-2-propylimidazole-5-carboxylate;

Suppliers and Price of OlMesartan interMediate iMpurity II

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Acetyl-2-propyl-1H-Imidazole-4-carboxylicAcidEthylEster
10mg
$ 1120.00

Matrix Scientific
5-Acetyl-2-propyl-3H-imidazole-4-carboxylic acid ethyl ester 95%+
1g
$ 1768.00

Crysdot
Ethyl5-acetyl-2-propyl-1H-imidazole-4-carboxylate 97%
25mg
$ 2850.00

Acrotein
Ethyl5-acetyl-2-propyl-1H-imidazole-4-carboxylate 97%
0.5g
$ 400.00

Total 23 raw suppliers

Chemical Property of OlMesartan interMediate iMpurity II

Chemical Property:

Melting Point:80-82oC
Boiling Point:438.5±30.0 °C(Predicted)
PKA:9.05±0.10(Predicted)
PSA：72.05000
Density:1.142±0.06 g/cm3(Predicted)
LogP:1.74150
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Acetyl-2-propyl-1H-Imidazole-4-carboxylicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5-Acetyl-2-propyl-1H-Imidazole-4-carboxylic Acid Ethyl Ester is used in the synthetic preparation of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds.

Technology Process of OlMesartan interMediate iMpurity II

There total 3 articles about OlMesartan interMediate iMpurity II which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 144690-06-2
4-acetyl-2-propylimidazole-5-carbonitrile

: 144690-07-3
ethyl 4-acetyl-2-propylimidazole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 6N aq. HCl / 8 h / Heating

2: HCl / 16 h / Ambient temperature

With hydrogenchloride;
DOI:10.1021/jm950450f

Reference yield:

: 51802-42-7
2-propylimidazole-4,5-dicarbonitrile

: 144690-07-3
ethyl 4-acetyl-2-propylimidazole-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / tetrahydrofuran / 0.5 h / 10 - 15 °C

2: 6N aq. HCl / 8 h / Heating

3: HCl / 16 h / Ambient temperature

With hydrogenchloride; In tetrahydrofuran;
DOI:10.1021/jm950450f