3-Methylglutarimide

Base Information

Chemical Name:3-Methylglutarimide
CAS No.:25077-26-3
Molecular Formula:C6H9 N O2
Molecular Weight:127.143
Hs Code.:2925190090
NSC Number:39842
UNII:16FA9AZ3FW
DSSTox Substance ID:DTXSID60179766
Nikkaji Number:J509.210H
Wikidata:Q27251812
Mol file:25077-26-3.mol

Synonyms:3-methylglutarimide;3-MG-imide

Suppliers and Price of 3-Methylglutarimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-methylpiperidine-2,6-dione
50mg
$ 155.00

AccelPharmtech
4-methyl-2,6-Piperidinedione 97.00%
5G
$ 1700.00

Total 5 raw suppliers

Chemical Property of 3-Methylglutarimide

Chemical Property:

Vapor Pressure:0.00441mmHg at 25°C
Melting Point:144-145 °C
Boiling Point:277.9°Cat760mmHg
PKA:11.78±0.40(Predicted)
Flash Point:138.8°C
PSA：46.17000
Density:1.101g/cm³
LogP:0.38790
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:127.063328530
Heavy Atom Count:9
Complexity:137

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-methylpiperidine-2,6-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(=O)NC(=O)C1

Technology Process of 3-Methylglutarimide

There total 2 articles about 3-Methylglutarimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35931-93-2
citronellyl nitrile

: 67-64-1
acetone

: 25077-26-3
3-methyl glutarimide

: 99356-87-3
(R)-5-cyano-4-methyl-valeric acid

: 498-21-5,636-60-2
2-methylbutanedioic acid

Guidance literature:: Produkt5:4-<5-Cyan-4-methyl-valerylamino>-3-methyl-but-3-ennitril;
DOI:10.1021/jo01127a002

Reference yield:

: 110-86-1
pyridine

: 75-07-0,9002-91-9
acetaldehyde

: 372-09-8
cyanoacetic acid

: 25077-26-3
3-methyl glutarimide

: 1190-76-7,627-26-9
(Z)-2-butenenitrile

: 4786-20-3,627-26-9
crotononitrile

: 50870-55-8
(E+Z)-4-cyano-3-methyl-4-hexenenitrile

Guidance literature:: erst in der Kaelte, zuletzt bei 60grad;

Reference yield: 73.0%

: C₂₂H₂₉BrMgOSi

: 25077-26-3
3-methyl glutarimide

: (4S,6R)-6-[(Z)-6-(tert-Butyl-diphenyl-silanyloxy)-hex-4-enyl]-4-methyl-piperidin-2-one

Guidance literature:: 3-methyl glutarimide; With methylmagnesium chloride; In tetrahydrofuran; at 0 - 20 ℃;

C₂₂H₂₉BrMgOSi; In tetrahydrofuran; at 20 ℃; for 12h;

With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; at 20 ℃; for 0.75h; Further stages.;
DOI:10.1021/jo062533h