1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione

Base Information

Chemical Name:1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione
CAS No.:153631-19-7
Molecular Formula:C32H34N2O8
Molecular Weight:574.631
Hs Code.:
Mol file:153631-19-7.mol

1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione

Synonyms:5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-methyl-5-methyluridine;5'-O-(4,4'-dimethoxytrityl)-2'-O,5-dimethyluridine;

Suppliers and Price of 1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
5?-O-DMT-2?-O-methyl-5-methyluridine
1 g
$ 873.00

Medical Isotopes, Inc.
5?-O-DMT-2?-O-methyl-5-methyluridine
250 mg
$ 498.00

Biosynth Carbosynth
5'-O-DMT-2'-O-methyl-5-methyluridine
2 g
$ 420.00

Biosynth Carbosynth
5'-O-DMT-2'-O-methyl-5-methyluridine
1 g
$ 235.00

Biosynth Carbosynth
5'-O-DMT-2'-O-methyl-5-methyluridine
500 mg
$ 160.00

Biosynth Carbosynth
5'-O-DMT-2'-O-methyl-5-methyluridine
250 mg
$ 100.00

Biosynth Carbosynth
5'-O-DMT-2'-O-methyl-5-methyluridine
100 mg
$ 65.00

Total 16 raw suppliers

Chemical Property of 1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione

Chemical Property:

PKA:9.55±0.10(Predicted)
PSA：121.24000
Density:1.33±0.1 g/cm3(Predicted)
LogP:3.14420

Purity/Quality:

97% ^*data from raw suppliers

5?-O-DMT-2?-O-methyl-5-methyluridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5''-O-DMT-2''-O-methyl-5-methyluridine is a uridine-derived oligonucleoside (U829910) used in the synthetic preparation of nucleic acids.

Technology Process of 1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione

There total 22 articles about 1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 55486-09-4
2'-O-Methyl-5-methyluridine

: 153631-19-7
5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyluridine

Guidance literature:: With dmap; In pyridine; at 20 ℃;
DOI:10.1002/cbic.201700492

Reference yield: 71.0%

: 153631-18-6
3-(2-cyanoethyl)-1-<5-O--2-O-methyl-β-D-ribofuranosyl>-5-methyl-1H,3H-pyrimidine-2,4-dione

: 153631-19-7
5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyluridine

Guidance literature:: With potassium tert-butylate; In dichloromethane; for 1.5h; Ambient temperature;
DOI:10.1002/jhet.5570300522

Reference yield:

: 22423-26-3
O-2,2'-cyclo-5-methyluridine

: 153631-19-7
5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyluridine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; DMAP / 20 °C

2: dimethylformamide / 2.5 h / 100 °C

With pyridine; dmap; In N,N-dimethyl-formamide;
DOI:10.1021/jo030086p