Piperidine, 1-(4-phenyl-2-selenazolyl)-

Base Information

• Chemical Name: Piperidine, 1-(4-phenyl-2-selenazolyl)-
• CAS No.: 154437-01-1
• Molecular Formula: C₁₄H₁₆N₂Se
• Molecular Weight: 291.254
• DSSTox Substance ID: DTXSID30469404
• Nikkaji Number: J2.239.725G
• Wikidata: Q82297108
• Mol file: 154437-01-1.mol

Synonyms:Piperidine, 1-(4-phenyl-2-selenazolyl)-;154437-01-1;4-phenyl-2-piperidinoselenazole;DTXSID30469404

Chemical Property of Piperidine, 1-(4-phenyl-2-selenazolyl)-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 292.04787
• Heavy Atom Count: 17
• Complexity: 234

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)C2=NC(=C[Se]2)C3=CC=CC=C3

Technology Process of Piperidine, 1-(4-phenyl-2-selenazolyl)-

There total 4 articles about Piperidine, 1-(4-phenyl-2-selenazolyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

N-(selenocarbamido)piperidine (61934-60-9) + α-bromoacetophenone (70-11-1) → 4-phenyl-2-piperidino-1,3-selenazole (154437-01-1)

Guidance literature:

In ethanol; for 0.666667h; Heating;

DOI:10.1080/10426509908031628

Reference yield: 32.0%

N-(selenocarbamido)piperidine (61934-60-9) + acetophenone (98-86-2) → 4-phenyl-2-piperidino-1,3-selenazole (154437-01-1)

Guidance literature:

With iron(III) chloride; In ethanol; Heating;

DOI:10.1248/cpb.53.1439

Reference yield:

piperidine (110-89-4) → 4-phenyl-2-piperidino-1,3-selenazole (154437-01-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 50 percent / KOH / diethyl ether / 10 °C

2: 40 percent / H₂Se; conc. aq. NH₃ / ethanol / 6 h / 60 °C

3: 65 percent / ethanol / 0.67 h / Heating

With potassium hydroxide; ammonium hydroxide; hydrogen selenide; In diethyl ether; ethanol; 1: Condensation / 2: Addition / 3: Condensation;

DOI:10.1080/10426509908031628

upstream raw materials:

N-(selenocarbamido)piperidine

α-bromoacetophenone

acetophenone

piperidine