Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)-

Base Information

Chemical Name:Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)-
CAS No.:154639-75-5
Molecular Formula:C10H12FNO2S
Molecular Weight:229.275
Hs Code.:
DSSTox Substance ID:DTXSID60434923
Mol file:154639-75-5.mol

Synonyms:154639-75-5;Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)-;SCHEMBL6535624;DTXSID60434923;CQBGMEVMWSNQLD-UHFFFAOYSA-N;1-(4-fluoro-2-methylaminophenyl)-2-methylsulphinylethanone

Suppliers and Price of Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)-

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:229.05727796
Heavy Atom Count:15
Complexity:260

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(C=CC(=C1)F)C(=O)CS(=O)C

Technology Process of Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)-

There total 5 articles about Ethanone, 1-[4-fluoro-2-(methylamino)phenyl]-2-(methylsulfinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123732-75-2
1-(4-fluoro-2-methylaminophenyl)-2-(methylthio)ethanone

: 154639-75-5
1-(4-fluoro-2-methylaminophenyl)-2-methylsulfinylethanone

Guidance literature:: With m-chloroperoxybenzoic acid; In dichloromethane;

Reference yield:

: 2252-51-9
2-choro-4-fluorobenzoic acid

: 154639-75-5
1-(4-fluoro-2-methylaminophenyl)-2-methylsulfinylethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / copper (powder), copper(II) chloride dihydrate / H₂O / 1) 75 - 80 deg C, 30 min; 2) reflux, 5 h

2: sodium carbonate / toluene; H₂O / 19 h / Ambient temperature

3: 1.) sodium hydride / 1) toluene, 70 - 75 deg C, 1 h; 2) toluene, 1 h, 30 deg C

With copper; sodium hydride; sodium carbonate; copper dichloride; In water; toluene;

Reference yield:

: 128992-62-1
4-fluoro-N-methylanthranilic acid

: 154639-75-5
1-(4-fluoro-2-methylaminophenyl)-2-methylsulfinylethanone

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / toluene; H₂O / 19 h / Ambient temperature

2: 1.) sodium hydride / 1) toluene, 70 - 75 deg C, 1 h; 2) toluene, 1 h, 30 deg C

With sodium hydride; sodium carbonate; In water; toluene;