4-formyl-6-methoxy-3-nitrophenoxyacetic acid

Base Information

• Chemical Name: 4-formyl-6-methoxy-3-nitrophenoxyacetic acid
• CAS No.: 90429-09-7
• Molecular Formula: C10H9 N O7
• Molecular Weight: 255.184
• Mol file: 90429-09-7.mol

Synonyms:Aceticacid, (4-formyl-2-methoxy-5-nitrophenoxy)- (9CI);4-Formyl-6-methoxy-3-nitrophenoxyacetic acid

Chemical Property of 4-formyl-6-methoxy-3-nitrophenoxyacetic acid

Chemical Property:

• Vapor Pressure: 1.27E-11mmHg at 25°C
• Boiling Point: 519.6°Cat760mmHg
• Flash Point: 268.1°C
• PSA: 118.65000
• Density: 1.482g/cm³
• LogP: 1.40250

Purity/Quality:

99% ^*data from raw suppliers

4-Formyl-6-methoxy-3-nitrophenoxyaceticacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-formyl-6-methoxy-3-nitrophenoxyacetic acid

There total 6 articles about 4-formyl-6-methoxy-3-nitrophenoxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

tert-butyl 2-(4-formyl-2-methoxyphenoxy)acetate (179002-91-6) → 2-(4-formyl-2-methoxy-5-nitrophenoxy)acetic acid (90429-09-7)

Guidance literature:

With nitric acid; In acetic anhydride; 0 deg C, 2 h; rt, 4 h;

DOI:10.1021/jo961602x

Reference yield: 80.0%

ethyl 2-(4-formyl-2-methoxyphenoxy)acetate (51264-70-1) → 2-(4-formyl-2-methoxy-5-nitrophenoxy)acetic acid (90429-09-7)

Guidance literature:

With nitric acid; acetic anhydride; at 0 - 20 ℃; for 6h;

DOI:10.1002/chem.201900750

Reference yield: 68.0%

(4-formyl-2-methoxyphenoxy)acetic acid (1660-19-1) → 2-(4-formyl-2-methoxy-5-nitrophenoxy)acetic acid (90429-09-7)

Guidance literature:

With nitric acid; acetic acid; In water; at 0 - 20 ℃;

DOI:10.1039/b927215c

upstream raw materials:

tert-butyl 2-(4-formyl-2-methoxyphenoxy)acetate

vanillin

(4-formyl-2-methoxyphenoxy)acetic acid

ethyl 2-(4-formyl-2-methoxyphenoxy)acetate

Downstream raw materials:

2-(4-formyl-2-methoxy-5-nitrophenoxy)-N-(2-(N-tert-butoxycarbonylamino)ethylamine)acetamide

2-(4-hydroxymethyl-2-methoxy-5-nitrophenoxy)-N-(2-(N-tert-butoxycarbonylamino)ethylamine)acetamide

N-benzyl-(4-formyl-2-methoxy-5-nitrophenoxy)acetamide