Ethyl (4-formyl-2-methoxyphenoxy)acetate

Base Information

• Chemical Name: Ethyl (4-formyl-2-methoxyphenoxy)acetate
• CAS No.: 51264-70-1
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID20359527
• Wikidata: Q82140775
• Mol file: 51264-70-1.mol

Synonyms:51264-70-1;ethyl (4-formyl-2-methoxyphenoxy)acetate;ethyl 2-(4-formyl-2-methoxyphenoxy)acetate;4-Formyl-2-Methoxy-Phenoxy-Acetic Acid Ethyl Ester;MFCD01764358;Oprea1_370649;Oprea1_835552;4-FORMYL-2-METHOXY-PHENOXY-ACETICACIDETHYLESTER;SCHEMBL3788224;DTXSID20359527;BCA26470;STK347064;AKOS000180805;Ethyl(4-formyl-2-methoxyphenoxy)acetate;4-carbethoxymethoxy-3-methoxybenzaldehyde;AS-81450;ethyl2-(4-formyl-2-methoxyphenoxy)acetate;CS-0116538;FT-0703885;2-Methoxy-4-formyl-phenoxyessigsaureathylester;E81434;EN300-227944;(4-Formyl-2-methoxy-phenoxy)-acetic acid ethyl ester;Z54066001

Chemical Property of Ethyl (4-formyl-2-methoxyphenoxy)acetate

Chemical Property:

• Vapor Pressure: 2.57E-05mmHg at 25°C
• Melting Point: 94 °C(Solv: cyclohexane (110-82-7))
• Refractive Index: 1.526
• Boiling Point: 358.3°Cat760mmHg
• Flash Point: 190.5°C
• PSA: 61.83000
• Density: 1.178g/cm³
• LogP: 1.44960
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 238.08412354
• Heavy Atom Count: 17
• Complexity: 253

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-(4-formyl-2-methoxyphenoxy)acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)COC1=C(C=C(C=C1)C=O)OC

Technology Process of Ethyl (4-formyl-2-methoxyphenoxy)acetate

There total 11 articles about Ethyl (4-formyl-2-methoxyphenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

vanillin (121-33-5,8014-42-4) + ethyl bromoacetate (105-36-2) → ethyl 2-(4-formyl-2-methoxyphenoxy)acetate (51264-70-1)

Guidance literature:

With potassium carbonate; In acetone; for 14h; Reflux; Inert atmosphere;

DOI:10.1039/c5gc01334h

Reference yield: 96.0%

ethanol (64-17-5) + (4-formyl-2-methoxyphenoxy)acetic acid (1660-19-1) → ethyl 2-(4-formyl-2-methoxyphenoxy)acetate (51264-70-1)

Guidance literature:

With aluminum potassium sulfate dodecahydrate; In neat (no solvent); at 80 ℃; for 12h; Green chemistry;

Reference yield: 91.0%

C12H15NO5 (932796-56-0) → ethyl 2-(4-formyl-2-methoxyphenoxy)acetate (51264-70-1)

Guidance literature:

With copper(II) choride dihydrate; water; In acetonitrile; at 75 ℃; for 1.5h;

DOI:10.1055/s-0030-1259730

upstream raw materials:

vanillin

chloroacetic acid ethyl ester

ethyl bromoacetate

C₁₂H₁₅NO₅

Downstream raw materials:

(4-formyl-2-methoxyphenoxy)acetic acid

ethyl 2-(4-(2-(1H-benzo[d]imidazol-2-yl)-2-(N-(4-fluorophenyl)sulfamoyl)vinyl)-2-methoxyphenoxy)acetate

C₂₆H₂₃FN₂O₇S