2-(Diphenylmethylsilyl)ethanol

Base Information

• Chemical Name: 2-(Diphenylmethylsilyl)ethanol
• CAS No.: 40438-48-0
• Molecular Formula: C15H18 O Si
• Molecular Weight: 242.393
• Hs Code.: 2931900090
• European Community (EC) Number: 254-919-9
• DSSTox Substance ID: DTXSID60885799
• Nikkaji Number: J332.420F
• Wikidata: Q82864489
• Mol file: 40438-48-0.mol

Synonyms:2-(Methyldiphenylsilyl)ethanol;40438-48-0;2-(Diphenylmethylsilyl)ethanol;2-[methyl(diphenyl)silyl]ethanol;Ethanol, 2-(methyldiphenylsilyl)-;EINECS 254-919-9;(2-Hydroxyethyl)diphenylmethylsilane;SCHEMBL4340363;DTXSID60885799;MFCD00042928;2-(Methyldiphenylsilyl)ethanol, 99%;AKOS015915734;FT-0742161

Chemical Property of 2-(Diphenylmethylsilyl)ethanol

Chemical Property:

• Vapor Pressure: 1.49E-06mmHg at 25°C
• Refractive Index: n20/D 1.580(lit.)
• Boiling Point: 383.1°Cat760mmHg
• Flash Point: 155.2°C
• PSA: 20.23000
• Density: 1.04g/cm³
• LogP: 1.87170
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 242.112691728
• Heavy Atom Count: 17
• Complexity: 199

Purity/Quality:

99% ^*data from raw suppliers

2-(Methyldiphenylsilyl)ethanol 99% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 23-24/25

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](CCO)(C1=CC=CC=C1)C2=CC=CC=C2
• Uses: 2-(Methyldiphenylsilyl)ethanol (2-(Diphenylmethylsilyl)ethanol) may be used in the preparation of 2-diphenylmethylsilylethyldithiophosphorodichloridate.

Technology Process of 2-(Diphenylmethylsilyl)ethanol

There total 3 articles about 2-(Diphenylmethylsilyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl α-(methyldiphenylsilyl)acetate (77772-21-5) → diphenylmethylsilylethylethanol (40438-48-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Yield given; 1.) r.t., 1 h, 2.) reflux, 2 h;

DOI:10.1021/jo00101a029

Reference yield:

chloromethyldiphenylsilane (144-79-6) → diphenylmethylsilylethylethanol (40438-48-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LDA / 1.) THF, -78 deg C, 1 h, 2.) r.t., overnight

2: LiAlH₄ / diethyl ether / 1.) r.t., 1 h, 2.) reflux, 2 h

With lithium aluminium tetrahydride; lithium diisopropyl amide; In diethyl ether;

DOI:10.1021/jo00101a029

Reference yield:

→ diphenylmethylsilylethylethanol (40438-48-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating;

DOI:10.1016/S0040-4039(01)93285-X

upstream raw materials:

tert-butyl α-(methyldiphenylsilyl)acetate

chloromethyldiphenylsilane

Downstream raw materials:

Dithiophosphoric acid S,S'-bis-(4-methoxy-phenyl) ester O-[2-(methyl-diphenyl-silanyl)-ethyl] ester

(2-diphenylmethylsilylethoxy)bis(N,N-diisopropylamino)phosphine

bis<2-(methyldiphenylsilyl)ethyl> N,N-diisopropylphosphoramidite

bis<2-(methyldiphenylsilyl)ethyl> N,N-diethylphosphoramidite