1-tert-Butyl-2,4-diphenyl-1H-pyrrole

Base Information

Chemical Name:1-tert-Butyl-2,4-diphenyl-1H-pyrrole
CAS No.:15861-57-1
Molecular Formula:C20H21N
Molecular Weight:275.393
Hs Code.:2933990090
Mol file:15861-57-1.mol

Synonyms:Pyrrole,1-tert-butyl-2,4-diphenyl;1H-Pyrrole,1-(1,1-dimethylethyl)-2,4-diphenyl;1-t-Butyl-2,4-diphenylpyrrol;1-tert-butyl-2,4-diphenyl-pyrrole;1-tert-Butyl-2,4-diphenyl-1H-pyrrole;

Suppliers and Price of 1-tert-Butyl-2,4-diphenyl-1H-pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 1-tert-Butyl-2,4-diphenyl-1H-pyrrole

Chemical Property:

PSA：4.93000
LogP:5.57710

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-tert-Butyl-2,4-diphenyl-1H-pyrrole

There total 4 articles about 1-tert-Butyl-2,4-diphenyl-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 122-78-1
phenylacetaldehyde

: 75-64-9
tert-butylamine

: 15861-57-1
1-(tert-butyl)-2,4-diphenyl-1H-pyrrole

Guidance literature:: With iodine; In acetonitrile; at 60 ℃; for 8h;
DOI:10.1021/acs.joc.9b00596

Reference yield: 36.0%

: 495-45-4
dypnone

: 75-64-9
tert-butylamine

: 15861-57-1
1-(tert-butyl)-2,4-diphenyl-1H-pyrrole

Guidance literature:: With tetrabutylammomium bromide; oxygen; palladium diacetate; Trimethylacetic acid; In dimethyl sulfoxide; at 80 ℃; for 24h; Schlenk technique; Molecular sieve;
DOI:10.1016/j.tetlet.2020.151887

Reference yield:

: 98-86-2
acetophenone

: 15861-57-1
1-(tert-butyl)-2,4-diphenyl-1H-pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: titanium(IV) tetraethanolate / n-heptane / Dean-Stark; Heating

2: palladium diacetate; tetrabutylammomium bromide; oxygen; Trimethylacetic acid / dimethyl sulfoxide / 24 h / 80 °C / Schlenk technique; Molecular sieve

With titanium(IV) tetraethanolate; tetrabutylammomium bromide; oxygen; palladium diacetate; Trimethylacetic acid; In n-heptane; dimethyl sulfoxide;
DOI:10.1016/j.tetlet.2020.151887