trans-4-tert-butylcyclohexyl acetate

Base Information

• Chemical Name: trans-4-tert-butylcyclohexyl acetate
• CAS No.: 1900-69-2
• Molecular Formula: C12H22 O2
• Molecular Weight: 198.305
• Mol file: 1900-69-2.mol

Synonyms:Cyclohexanol,4-(1,1-dimethylethyl)-, acetate, trans- (9CI); Cyclohexanol, 4-tert-butyl-,acetate, trans- (8CI); trans-4-tert-Butyl-1-acetoxycyclohexane;trans-4-tert-Butylcyclohexyl acetate; trans-p-tert-Butylcyclohexyl acetate

Chemical Property of trans-4-tert-butylcyclohexyl acetate

Chemical Property:

• PSA: 26.30000
• LogP: 3.15440

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trans-4-tert-butylcyclohexyl acetate

There total 9 articles about trans-4-tert-butylcyclohexyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

trans-4-tert-butylcyclohexanol (21862-63-5) + acetic anhydride (108-24-7) → trans-4-tert-butylcyclohexyl acetate (1900-69-2)

Guidance literature:

With pyridine; at 25 ℃;

DOI:10.1021/acscatal.0c03423

Reference yield: 54.0%

methanesulfonic acid 4-tert-butylcyclohexyl ester (18508-91-3) + cesium acetate (3396-11-0) → trans-4-tert-butylcyclohexyl acetate (1900-69-2)

Guidance literature:

In N,N-dimethyl-formamide; at 105 ℃; for 24h;

Reference yield:

4-(1,1-dimethylethyl)-cyclohexanol (98-52-2) + acetic anhydride (108-24-7) → trans-4-tert-butylcyclohexyl acetate (1900-69-2) + cis-4-tert-butylcyclohexyl acetate (10411-92-4)

Guidance literature:

With β-CD acetate; Porcine Pancreas Lipase; In hexane; chloroform; at 56 ℃; for 120h; Further Variations:; Reagents; Reaction partners; Product distribution;

upstream raw materials:

trans-4-tert-butylcyclohexanol

acetic anhydride

trans-4-tert-butylcyclohexanol methyl ether

perchlorate d'acetyle

Downstream raw materials:

tert-butylcyclohexane

cis-4-tert-butylcyclohexyl acetate

Acetic acid 4-tert-butyl-4-fluoro-cyclohexyl ester

Acetic acid 4-tert-butyl-4-hydroxy-cyclohexyl ester

Refernces

• 1、 Manohar, Balaraman,Divakar, Soundar. "Porcine pancreas lipase catalysed acetylation of β-cyclodextrin anchored 4-t-butylcyclohexanol". . p. 2661 - 2665. Retrieved 2007/10/03.
• 2、 Huffman, John W.,Desai, Ranjit C.. "A PROCEDURE FOR ALCOHOL INVERSION USING CESIUM ACETATE". . p. 553 - 558. Retrieved 2007/10/02.