Cyclohexane,1-(1,1-dimethylethyl)-4-methoxy-trans-

Base Information

• Chemical Name: Cyclohexane,1-(1,1-dimethylethyl)-4-methoxy-trans-
• CAS No.: 15876-31-0
• Molecular Formula: C11H22 O
• Molecular Weight: 170.295
• Hs Code.: 2909209000
• Mol file: 15876-31-0.mol

Synonyms:Ether,4-tert-butylcyclohexyl methyl, trans- (8CI); trans-4-tert-Butylcyclohexylmethyl ether

Chemical Property of Cyclohexane,1-(1,1-dimethylethyl)-4-methoxy-trans-

Chemical Property:

• PSA: 9.23000
• LogP: 3.23770

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexane,1-(1,1-dimethylethyl)-4-methoxy-trans-

There total 6 articles about Cyclohexane,1-(1,1-dimethylethyl)-4-methoxy-trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tert-butyl-1,1-dimethoxy-cyclohexane (944-19-4) → trans-4-tert-butylcyclohexanol methyl ether (15876-31-0) + cis-4-tert-butylcyclohexanol methyl ether (15875-99-7)

Guidance literature:

With trimethylsilan; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 29 ℃; for 16h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(01)93263-6

Reference yield:

trans-4-tert-butylcyclohexanol (21862-63-5) + methyl iodide (74-88-4) → trans-4-tert-butylcyclohexanol methyl ether (15876-31-0)

Guidance literature:

With sodium hydride;

Reference yield:

4-(1,1-dimethylethyl)-cyclohexanol (98-52-2) + methyl iodide (74-88-4) → trans-4-tert-butylcyclohexanol methyl ether (15876-31-0) + cis-4-tert-butylcyclohexanol methyl ether (15875-99-7)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction. Title compound not separated from byproducts; 1) THF, 45 - 50 deg C, 2) THF, 40 min;

DOI:10.1016/S0040-4020(01)81971-2

upstream raw materials:

trans-4-tert-butylcyclohexanol

dimethyl sulfate

methyl iodide

iodomethane-d3

Downstream raw materials:

trans-4-tert-butylcyclohexyl acetate

methanolate

4-tert-butylcylohexene

4-tercbutyl-cyclohexanone