2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid, 3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-, 1,1-dimethylethyl ester

Base Information

Chemical Name:2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid, 3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-, 1,1-dimethylethyl ester
CAS No.:160388-25-0
Molecular Formula:C51H74N6O10
Molecular Weight:931.183
Hs Code.:
Mol file:160388-25-0.mol

2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid,
3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-,
1,1-dimethylethyl ester

Synonyms:

Suppliers and Price of 2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid, 3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid, 3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid, 3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-, 1,1-dimethylethyl ester

There total 11 articles about 2-Oxa-3,9,14,20,25,31-hexaazadotriacontan-32-oic acid, 3-acetyl-10,13,21,24-tetraoxo-14,25-bis(phenylmethoxy)-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 75-36-5
acetyl chloride

: 160388-24-9
1-(tert-Butoxycarbonyl)-7,18,29-tris(benzyloxy)-8,11,19,22-tetraoxo-1,7,12,18,23,29-hexaazanonacosane

: 160388-25-0
1-(tert-Butoxycarbonyl)-7,18,29-tris(benzyloxy)-8,11,19,22,30-pentaoxo-1,7,12,18,23,29-hexaazahentriacontane

Guidance literature:: With triethylamine; In dichloromethane; for 24h;
DOI:10.1021/jo00106a022

Reference yield:

: 100-39-0
benzyl bromide

: 106339-54-2
1-(tert-Butoxycarbonyl)-7,18,29-trihydroxy-8,11,19,22,30-pentaoxo-1,7,12,18,23,29-hexaazahentriacontane

: 160388-25-0
1-(tert-Butoxycarbonyl)-7,18,29-tris(benzyloxy)-8,11,19,22,30-pentaoxo-1,7,12,18,23,29-hexaazahentriacontane

Guidance literature:: With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 24h;

Reference yield:

: 129245-21-2
O-benzyl-N-(5-aminopentyl)-N-(tert-butoxycarbonyl)hydroxylamine

: 160388-25-0
1-(tert-Butoxycarbonyl)-7,18,29-tris(benzyloxy)-8,11,19,22,30-pentaoxo-1,7,12,18,23,29-hexaazahentriacontane

Guidance literature:: Multi-step reaction with 9 steps

1: TFA / CH₂Cl₂ / 30 h / Ambient temperature

2: tetrahydrofuran / 24 h

3: 88 percent / pyridine / 1.5 h / 80 - 86 °C

4: CH₂Cl₂ / 1 h

5: CH₂Cl₂ / 12 h

6: 81 percent / pyridine / 2 h / 81 °C

7: CH₂Cl₂ / 1 h

8: CH₂Cl₂ / 24 h

9: 87 percent / Et₃N / CH₂Cl₂ / 24 h

With pyridine; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00106a022