3-Ethylpiperidin-2-one

Base Information

Chemical Name:3-Ethylpiperidin-2-one
CAS No.:165385-85-3
Molecular Formula:C7H13NO
Molecular Weight:127.186
Hs Code.:
European Community (EC) Number:847-659-8
DSSTox Substance ID:DTXSID80447939
Nikkaji Number:J699.562D
ChEMBL ID:CHEMBL356082
Mol file:165385-85-3.mol

Synonyms:3-ethylpiperidin-2-one;165385-85-3;2-Piperidinone, 3-ethyl-;CHEMBL356082;SCHEMBL1967238;DTXSID80447939;AKOS006347263;SB42214;EN300-659036;Z1203731521

Suppliers and Price of 3-Ethylpiperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-Ethylpiperidin-2-one

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:127.099714038
Heavy Atom Count:9
Complexity:112

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CCCNC1=O

Technology Process of 3-Ethylpiperidin-2-one

There total 1 articles about 3-Ethylpiperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5693-62-9
2,3,4,5-tetrahydro-6-methoxypyridine

: 165385-85-3
(+/-)-3-ethyl-2-piperidone

Guidance literature:: Multi-step reaction with 3 steps

1.1: t-BuLi / hexane; tetrahydrofuran / 0.25 h / -78 - 0 °C

1.2: 68 percent / hexane; tetrahydrofuran / -78 - 20 °C

2.1: 81 percent / aq. HCl / CHCl₃

3.1: 91 percent / aq. K₂CO₃ / methanol / 24 h

With hydrogenchloride; tert.-butyl lithium; potassium carbonate; In tetrahydrofuran; methanol; hexane; chloroform;
DOI:10.1055/s-2006-939726

Reference yield: 96.0%

: 165385-85-3
(+/-)-3-ethyl-2-piperidone

: 40888-21-9
methyl (E)-3-(2′-iodophenyl)acrylate

: (E)-methyl 3-(2-(3-ethyl-2-oxopiperidin-1-yl)phenyl)acrylate

Guidance literature:: With copper; potassium carbonate; In toluene; at 150 ℃; for 72h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.5b02277

Reference yield: 89.0%

: 165385-85-3
(+/-)-3-ethyl-2-piperidone

: 100-39-0
benzyl bromide

: 95936-18-8
3-ethyl-1-(phenylmethyl)-2-piperidinone

Guidance literature:: With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; Ambient temperature;
DOI:10.1021/jm960561u