[1,1'-Biphenyl]-4-acetic acid, a-oxo-, methyl ester

Base Information

• Chemical Name: [1,1'-Biphenyl]-4-acetic acid, a-oxo-, methyl ester
• CAS No.: 16738-11-7
• Molecular Formula: C15H12O3
• Molecular Weight: 240.258
• Mol file: 16738-11-7.mol

Synonyms:

Chemical Property of [1,1'-Biphenyl]-4-acetic acid, a-oxo-, methyl ester

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

Methyl2-([1,1'-biphenyl]-4-yl)-2-oxoacetate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1,1'-Biphenyl]-4-acetic acid, a-oxo-, methyl ester

There total 12 articles about [1,1'-Biphenyl]-4-acetic acid, a-oxo-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ methyl 2-([1,1'-biphenyl]-4-yl)-2-oxoacetate (16738-11-7)

Guidance literature:

With iodine; In tetrahydrofuran; at 20 ℃;

Reference yield: 70.0%

methanol (67-56-1) + 4-ethynyl-1,1'-biphenyl (29079-00-3) → methyl 2-([1,1'-biphenyl]-4-yl)-2-oxoacetate (16738-11-7)

Guidance literature:

With iodosylbenzene; silver trifluoromethanesulfonate; In 1,2-dichloro-ethane; at 40 ℃; for 1h; Reagent/catalyst; Solvent; Temperature; Time;

DOI:10.1021/acs.orglett.5b03484

Reference yield: 70.0%

methanol (67-56-1) + biphenyl-4-acetaldehyde (92-91-1) → methyl 2-([1,1'-biphenyl]-4-yl)-2-oxoacetate (16738-11-7)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine; 4-nitro-phenol; oxygen; potassium iodide; for 11.5h; Electrochemical reaction;

DOI:10.1002/chem.201302307

upstream raw materials:

methanol

ethyl (4-phenylphenyl)glyoxylate

-methoxy-essigsaeure-methylester

biphenyl-4-acetaldehyde

Downstream raw materials:

methyl 2-([1,1'-biphenyl]-4-yl)-2-hydroxy-3-(2-phenyloxazol-5-yl)propanoate

1-[(1,1′-biphenyl)-4-yl]-3-phenylpropane-1,3-dione