8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione

Base Information

Chemical Name:8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione
CAS No.:77796-17-9
Molecular Formula:C16H13F2NS
Molecular Weight:289.349
Hs Code.:
DSSTox Substance ID:DTXSID30999014

Synonyms:BRN 4507783;VUFB-14044;8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione;1,3,4,5-Tetrahydro-8-fluoro-3-(4-fluorophenyl)-2H-1-benzazepine-2-thione;2H-1-Benzazepine-2-thione, 1,3,4,5-tetrahydro-8-fluoro-3-(4-fluorophenyl)-;77796-17-9;C16H13F2NS;DTXSID30999014;C16-H13-F2-N-S;LS-28020;8-Fluoro-5-(4-fluorophenyl)-4,5-dihydro-3H-1-benzazepine-2-thiol

Suppliers and Price of 8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione

Chemical Property:

Vapor Pressure:3.12E-05mmHg at 25°C
Boiling Point:355.5°Cat760mmHg
Flash Point:168.8°C
Density:1.31g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:289.07367692
Heavy Atom Count:20
Complexity:354

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=S)NC2=C(C1C3=CC=C(C=C3)F)C=CC(=C2)F

Technology Process of 8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione

There total 2 articles about 8-Fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68351-37-1
8-fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-one

: 77796-17-9
8-fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione

Guidance literature:: With tetraphosphorus decasulfide; In pyridine; for 0.75h; Heating;
DOI:10.1135/cccc19810148

Reference yield:

: 68351-22-4
7-fluoro-4-(4-fluorophenyl)-1-tetralone oxime

: 77796-17-9
8-fluoro-5-(4-fluorophenyl)-1,3,4,5-tetrahydro-1-benzazepin-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / polyphosphoric acid / 130 °C

2: P₂S₅ / pyridine / 0.75 h / Heating

With PPA; tetraphosphorus decasulfide; In pyridine;
DOI:10.1135/cccc19810148