2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine

Base Information

Chemical Name:2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine
CAS No.:175602-48-9
Molecular Formula:C21H29NO
Molecular Weight:311.467
Hs Code.:
DSSTox Substance ID:DTXSID50570460
Nikkaji Number:J708.630J
Wikidata:Q82457912

Synonyms:175602-48-9;2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine;DTXSID50570460

Suppliers and Price of 2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine

Chemical Property:

XLogP3:6.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:311.224914549
Heavy Atom Count:23
Complexity:378

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=CC=C1)C2=C(C=C(C=C2OC)C(C)(C)C)C(C)(C)C

Technology Process of 2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine

There total 3 articles about 2-(2,4-Di-tert-butyl-6-methoxyphenyl)-3-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 3430-17-9
2-bromo-3-picoline

: 175602-46-7
2,4-di-tert-butyl-6-methoxyphenylboronic acid

: 175602-48-9
2-(2,4-Di-tert-butyl-6-methoxy-phenyl)-3-methyl-pyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; In 1,2-dimethoxyethane; tert-butyl alcohol; for 16h; Heating;
DOI:10.1016/0040-4039(95)02343-7

Reference yield: 30.0%

: 175602-46-7
2,4-di-tert-butyl-6-methoxyphenylboronic acid

: 68039-43-0
1,3-di-tert-butyl-5-methoxybenzene

: 175602-48-9
2-(2,4-Di-tert-butyl-6-methoxy-phenyl)-3-methyl-pyridine

Guidance literature:: With 2-bromo-3-picoline; tetrakis(triphenylphosphine) palladium⁽⁰⁾; 18-crown-6 ether; potassium tert-butylate; In 1,2-dimethoxyethane; tert-butyl alcohol; at 95 ℃;
DOI:10.1021/jo980646y

Reference yield: 18.0%

: 3430-17-9
2-bromo-3-picoline

: 175602-46-7
2,4-di-tert-butyl-6-methoxyphenylboronic acid

: 68039-43-0
1,3-di-tert-butyl-5-methoxybenzene

: 175602-48-9
2-(2,4-Di-tert-butyl-6-methoxy-phenyl)-3-methyl-pyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; In 1,2-dimethoxyethane; tert-butyl alcohol; at 95 ℃; for 0.25h;
DOI:10.1021/jo980646y