2-Chloro-6-hydroxy-benzoic acid Methyl ester

Base Information

• Chemical Name: 2-Chloro-6-hydroxy-benzoic acid Methyl ester
• CAS No.: 176750-70-2
• Molecular Formula: C8H7ClO3
• Molecular Weight: 186.595
• Hs Code.: 2918290090
• Mol file: 176750-70-2.mol

Synonyms:2-Chlor-6-hydroxy-4-methyl-chinolin;2-Chloro-4-methyl-quinolin-6-ol;2-Chlor-4-methyl-6-hydroxychinolin;2-chloro-6-hydroxy-benzoic acid methyl ester;2-chloro-6-hydroxy-4-methyl-quinoline;2-Chlor-6-hydroxy-benzoesaeure-methylester;

Chemical Property of 2-Chloro-6-hydroxy-benzoic acid Methyl ester

Chemical Property:

• Boiling Point: 250.4±20.0 °C(Predicted)
• PKA: 8.79±0.10(Predicted)
• PSA: 46.53000
• Density: 1.354±0.06 g/cm3(Predicted)
• LogP: 1.83220
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

Methyl2-chloro-6-hydroxybenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chloro-6-hydroxy-benzoic acid Methyl ester

There total 1 articles about 2-Chloro-6-hydroxy-benzoic acid Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

methanol (67-56-1) + 6-chloro-2-hydroxybenzoic acid (56961-31-0) → methyl 2-chloro-6-hydroxybenzoate (176750-70-2)

Guidance literature:

With sulfuric acid; at 85 ℃; for 30h; Inert atmosphere;

Reference yield: 97.0%

methyl 2-chloro-6-hydroxybenzoate (176750-70-2) + chloromethyl methyl ether (107-30-2) → methyl 2-chloro-6-(methoxymethyl)benzoate (902143-88-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; Cooling with ice;

Reference yield: 72.0%

2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetic acid (97980-71-7) + methyl 2-chloro-6-hydroxybenzoate (176750-70-2) → 2-chloro-6-(2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetoxy)benzoic acid

Guidance literature:

With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1016/j.ejmech.2010.10.034

upstream raw materials:

methanol

6-chloro-2-hydroxybenzoic acid

Downstream raw materials:

methyl 2-chloro-6-(methoxymethyl)benzoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 176750-70-2 2-Chloro-6-hydroxy-benzoic acid Methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send