1-Methoxy-2-indanol

Base Information

• Chemical Name: 1-Methoxy-2-indanol
• CAS No.: 71720-52-0
• Molecular Formula: C10H12 O2
• Molecular Weight: 164.204
• Hs Code.: 2909499000
• European Community (EC) Number: 275-901-7
• UNII: VN6E84YC8W
• DSSTox Substance ID: DTXSID90971558
• Nikkaji Number: J208.728F
• Mol file: 71720-52-0.mol

Synonyms:1-Methoxy-2-indanol;56175-44-1;1-methoxy-2,3-dihydro-1H-inden-2-ol;1-Methoxyindan-2-ol;71720-52-0;1H-Inden-2-ol, 2,3-dihydro-1-methoxy-, cis-;EINECS 275-901-7;1H-Inden-2-ol, 2,3-dihydro-1-methoxy-;1-Methoxy-2-indanol #;2-Indanol, 1-methoxy-;VN6E84YC8W;SCHEMBL5873471;ZHWPZRVYPHGXSF-UHFFFAOYSA-;DTXSID90971558;MFCD00003796;2,3-Dihydro-1-methoxy-1H-inden-2-ol;FT-0608002

Chemical Property of 1-Methoxy-2-indanol

Chemical Property:

• PSA: 29.46000
• LogP: 1.29110
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 158

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1C(CC2=CC=CC=C12)O

Technology Process of 1-Methoxy-2-indanol

There total 20 articles about 1-Methoxy-2-indanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 1-indene (95-13-6) → 1-methoxy-2,3-dihydro-1H-inden-2-ol (71720-52-0)

Guidance literature:

With dihydrogen peroxide; methyltrioxorhenium(VII); at 25 ℃; for 3h;

DOI:10.1039/a704496h

Reference yield: 93.0%

methanol (67-56-1) + 2,3-epoxyindene (768-22-9) → trans-1-methoxy-2-hydroxyindan (56175-44-1,56175-45-2,71192-96-6,71720-52-0)

Guidance literature:

With sodium perchlorate; for 0.333333h; Ambient temperature; electrolysis;

DOI:10.1246/bcsj.68.2591

Reference yield: 89.0%

2-(1-methoxy-indan-2-yloxy)-tetrahydro-pyran → 1-methoxy-2,3-dihydro-1H-inden-2-ol (71720-52-0)

Guidance literature:

poly(4-vinylpyridinium) p-toluenesulfonate; In tetrahydrofuran; ethanol; at 75 ℃; for 40h;

DOI:10.1080/00397919808004423

upstream raw materials:

1-chloro-2-hydroxyindane

sodium methylate

methanol

1-indene

Downstream raw materials:

1-(2'-indanylidene)-2-indanone

2-indanone

5-nitro-1,3-dihydro-2H-inden-2-one

(1S,2R)-1-amino-2-indanol