2,4-Dihydroxy-3,5-dimethoxybenzaldehyde

Base Information

• Chemical Name: 2,4-Dihydroxy-3,5-dimethoxybenzaldehyde
• CAS No.: 182427-46-9
• Molecular Formula: C9H10O5
• Molecular Weight: 198.175
• DSSTox Substance ID: DTXSID30450438
• Nikkaji Number: J3.331.968A
• Wikidata: Q82270166
• Mol file: 182427-46-9.mol

Synonyms:2,4-Dihydroxy-3,5-dimethoxybenzaldehyde;182427-46-9;Benzaldehyde, 2,4-dihydroxy-3,5-dimethoxy-;SCHEMBL16385983;DTXSID30450438;4-hydroxy-3,5-dimethoxy-hydroxybenzaldehyde

Chemical Property of 2,4-Dihydroxy-3,5-dimethoxybenzaldehyde

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 198.05282342
• Heavy Atom Count: 14
• Complexity: 196

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C(C(=C1)C=O)O)OC)O

Technology Process of 2,4-Dihydroxy-3,5-dimethoxybenzaldehyde

There total 6 articles about 2,4-Dihydroxy-3,5-dimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-formyl-3-iodo-2,6-dimethoxyphenyl-2,2-dimethylpropanoate (1618668-33-9) → 2,4-dihydroxy-3,5-dimethoxybenzaldehyde (182427-46-9)

Guidance literature:

With copper(I) oxide; 2-pyridinealdoxime; cesium hydroxide monohydrate; tetrabutylammomium bromide; for 10h; Inert atmosphere;

DOI:10.3390/molecules181215613

Reference yield: 70.0%

methanol (67-56-1) + 3,5-dibromo-2,4-dihydroxy benzaldehyde (116096-91-4) + sodium methylate (124-41-4) → 2,4-dihydroxy-3,5-dimethoxybenzaldehyde (182427-46-9)

Guidance literature:

With copper(l) chloride; In N,N-dimethyl-formamide; at 100 ℃; for 4h;

DOI:10.21577/0103-5053.20180021

Reference yield: 54.0%

3,5-dibromo-2,4-dihydroxy benzaldehyde (116096-91-4) + sodium methylate (124-41-4) → 2,4-dihydroxy-3,5-dimethoxybenzaldehyde (182427-46-9)

Guidance literature:

With copper(l) chloride; In N,N-dimethyl-formamide; at 100 ℃; for 4h;

upstream raw materials:

3,5-dibromo-2,4-dihydroxy benzaldehyde

sodium methylate

2,4-Dihydroxybenzaldehyde

recorcinol