1H-Indole-4-carboxylic acid, 3-[[4-[[[(phenylmethoxy)carbonyl]amino]methyl]cyclohexyl]carbonyl]-, methyl ester, trans-

Base Information

Chemical Name:1H-Indole-4-carboxylic acid, 3-[[4-[[[(phenylmethoxy)carbonyl]amino]methyl]cyclohexyl]carbonyl]-, methyl ester, trans-
CAS No.:183283-78-5
Molecular Formula:C26H28N2O5
Molecular Weight:448.519
Hs Code.:
Mol file:183283-78-5.mol

Synonyms:

Suppliers and Price of 1H-Indole-4-carboxylic acid, 3-[[4-[[[(phenylmethoxy)carbonyl]amino]methyl]cyclohexyl]carbonyl]-, methyl ester, trans-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Indole-4-carboxylic acid, 3-[[4-[[[(phenylmethoxy)carbonyl]amino]methyl]cyclohexyl]carbonyl]-, methyl ester, trans-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Indole-4-carboxylic acid, 3-[[4-[[[(phenylmethoxy)carbonyl]amino]methyl]cyclohexyl]carbonyl]-, methyl ester, trans-

There total 6 articles about 1H-Indole-4-carboxylic acid, 3-[[4-[[[(phenylmethoxy)carbonyl]amino]methyl]cyclohexyl]carbonyl]-, methyl ester, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 39830-66-5
methyl 1H-indole-4-carboxylate

: 27687-13-4
trans-4-(N-carbobenzyloxy)aminomethyl-1-cyclohexane carbonyl chloride

: 925-90-6
ethylmagnesium bromide

: 183283-78-5
3-[(trans-1-(N-carbobenzyloxy)aminomethylcyclohex-4-yl)carbonyl]indole-4-carboxylic acid methyl ester

Guidance literature:: zinc(II) chloride; In methanol; dichloromethane;

Reference yield: 48.0%

: 183283-78-5
3-[(trans-1-(N-carbobenzyloxy)aminomethylcyclohex-4-yl)carbonyl]indole-4-carboxylic acid methyl ester

Guidance literature:

Reference yield:

: 1197-18-8
trans-4-aminomethyl-cyclohexyl-carboxylic acid

: 183283-78-5
3-[(trans-1-(N-carbobenzyloxy)aminomethylcyclohex-4-yl)carbonyl]indole-4-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 10percent aq. NaOH / 1 h

2: SOCl₂ / 0.5 h / 40 °C

3: 1.) EtMgBr, 2.) ZnCl₂

With sodium hydroxide; thionyl chloride; ethylmagnesium bromide; zinc(II) chloride;
DOI:10.1021/jm970389+