2-Chloro-3-methoxycyclohex-2-en-1-one

Base Information

Chemical Name:2-Chloro-3-methoxycyclohex-2-en-1-one
CAS No.:18369-67-0
Molecular Formula:C7H9ClO2
Molecular Weight:160.6
Hs Code.:
DSSTox Substance ID:DTXSID50525915
Wikidata:Q82393904
Mol file:18369-67-0.mol

Synonyms:2-Chloro-3-methoxycyclohex-2-en-1-one;18369-67-0;SCHEMBL10881461;DTXSID50525915

Suppliers and Price of 2-Chloro-3-methoxycyclohex-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Chloro-3-methoxycyclohex-2-en-1-one

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:160.0291072
Heavy Atom Count:10
Complexity:184

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=O)CCC1)Cl

Technology Process of 2-Chloro-3-methoxycyclohex-2-en-1-one

There total 2 articles about 2-Chloro-3-methoxycyclohex-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 504-02-9
1,3-cylohexanedione

: 18369-67-0
2-chloro-3-methoxycyclohex-2-enone

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / chloramine T / H₂O / 0.5 h / 5 - 10 °C

2: IR₁₂₀H ion-exchange resin / methanol / 4 h

With IR₁₂₀H ion-exchange resin; chloroamine-T; In methanol; water;

Reference yield:

: 932-23-0
2-chloro-cyclohexane-1,3-dione

: 149-73-5
trimethyl orthoformate

: 18369-67-0
2-chloro-3-methoxycyclohex-2-enone

Guidance literature:: With IR₁₂₀H ion-exchange resin; In methanol; for 4h; Yield given;

Reference yield: 83.0%

: 18369-67-0
2-chloro-3-methoxycyclohex-2-enone

: 1826-67-1
vinyl magnesium bromide

: 1619228-42-0
2-chloro-3-vinylcyclohex-2-en-1-one

Guidance literature:: 2-chloro-3-methoxycyclohex-2-enone; vinyl magnesium bromide; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;

With sulfuric acid; In tetrahydrofuran; water; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.tetlet.2014.05.074