Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-

Base Information

Chemical Name:Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-
CAS No.:183737-04-4
Molecular Formula:C14H20N6O5
Molecular Weight:352.34600
Hs Code.:
Mol file:183737-04-4.mol

Synonyms:N'-[9-((2R,3R,4R,5R)-4-Hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-N,N-dimethyl-formamidine;

Suppliers and Price of Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
N2-DMF-2'-O-methylguanosine
2 g
$ 650.00

Biosynth Carbosynth
N2-DMF-2'-O-methylguanosine
1 g
$ 375.00

Biosynth Carbosynth
N2-DMF-2'-O-methylguanosine
500 mg
$ 225.00

Biosynth Carbosynth
N2-DMF-2'-O-methylguanosine
250 mg
$ 150.00

Biosynth Carbosynth
N2-DMF-2'-O-methylguanosine
100 mg
$ 85.00

Total 18 raw suppliers

Chemical Property of Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-

Chemical Property:

PSA：138.09000
LogP:-1.39340

Purity/Quality:

99.3% ^*data from raw suppliers

N2-DMF-2'-O-methylguanosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-

There total 6 articles about Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₃₆N₆O₅Si

: 183737-04-4
N₂-dimethylaminomethylene-2'-O-methylguanosine

Guidance literature:: With triethylamine tris(hydrogen fluoride); triethylamine; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1016/j.bmcl.2009.11.016

Reference yield:

: 69304-44-5
3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine

: 183737-04-4
N₂-dimethylaminomethylene-2'-O-methylguanosine

Guidance literature:: Multi-step reaction with 4 steps

1: DMAP, Et₃N / CH₂Cl₂ / 8 h / Ambient temperature

2: BEMP / acetonitrile / 1.) 0 deg C, 10 min, 2.) r.t., 1.5 h

3: TBAF / tetrahydrofuran / 0.25 h

4: methanol / 12 h / Ambient temperature

With dmap; tetrabutyl ammonium fluoride; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; triethylamine; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;

Reference yield:

: 118-00-3
G

: 183737-04-4
N₂-dimethylaminomethylene-2'-O-methylguanosine

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / imidazole / dimethylformamide / 2 h / Ambient temperature

2: DMAP, Et₃N / CH₂Cl₂ / 8 h / Ambient temperature

3: BEMP / acetonitrile / 1.) 0 deg C, 10 min, 2.) r.t., 1.5 h

4: TBAF / tetrahydrofuran / 0.25 h

5: methanol / 12 h / Ambient temperature

With 1H-imidazole; dmap; tetrabutyl ammonium fluoride; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; triethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;