L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl- D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester

Base Information

Chemical Name:L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl- D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester
CAS No.:184295-95-2
Molecular Formula:C36H57N3O8Si2
Molecular Weight:716.035
Hs Code.:
Mol file:184295-95-2.mol

L-Serine,
O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl-
D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester

Synonyms:

Suppliers and Price of L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl- D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 4 raw suppliers

Chemical Property of L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl- D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl- D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester

There total 9 articles about L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(phenylmethoxy)carbonyl]-L-seryl- D-phenylalanyl-O-[(1,1-dimethylethyl)dimethylsilyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2448-45-5
Cbz-D-Phe

: 184295-95-2
(S)-2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionylamino]-3-phenyl-propionylamino}-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: N-methylmorpholine / CH₂Cl₂ / 0.25 h / -15 °C

2: CH₂Cl₂ / 0 - 20 °C

3: imidazole / CH₂Cl₂

4: H₂ / Pd/C / methanol

5: CH₂Cl₂ / 0 - 20 °C

6: imidazole / CH₂Cl₂

With 4-methyl-morpholine; 1H-imidazole; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/ja962859f

Reference yield:

: 63655-58-3
Z-D-Phe-Ser-OMe

: 184295-95-2
(S)-2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionylamino]-3-phenyl-propionylamino}-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: imidazole / CH₂Cl₂

2: H₂ / Pd/C / methanol

3: CH₂Cl₂ / 0 - 20 °C

4: imidazole / CH₂Cl₂

With 1H-imidazole; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/ja962859f

Reference yield:

: 41518-17-6
C₂₂H₂₅NO₆

: 184295-95-2
(S)-2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionylamino]-3-phenyl-propionylamino}-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: CH₂Cl₂ / 0 - 20 °C

2: imidazole / CH₂Cl₂

3: H₂ / Pd/C / methanol

4: CH₂Cl₂ / 0 - 20 °C

5: imidazole / CH₂Cl₂

With 1H-imidazole; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/ja962859f