Carbamic acid, [2-(4-aminophenyl)-1,6-dihydro-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-oxo- 1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

Base Information

• Chemical Name: Carbamic acid, [2-(4-aminophenyl)-1,6-dihydro-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-oxo- 1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester
• CAS No.: 184709-80-6
• Molecular Formula: C30H26F3N5O5
• Molecular Weight: 593.562
• Mol file: 184709-80-6.mol

Synonyms:

Chemical Property of Carbamic acid, [2-(4-aminophenyl)-1,6-dihydro-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-oxo- 1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

Chemical Property:

Purity/Quality:

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Useful:

Technology Process of Carbamic acid, [2-(4-aminophenyl)-1,6-dihydro-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-oxo- 1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

There total 1 articles about Carbamic acid, [2-(4-aminophenyl)-1,6-dihydro-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-oxo- 1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iron (7439-89-6) + 2-[5-benzyloxycarbonylamino-2-(4-nitrophenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide (184709-78-2) → 2-[2-(4-aminophenyl)-5-benzyloxycarbonylamino-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide (184709-80-6)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water;

Reference yield:

2-[2-(4-aminophenyl)-5-benzyloxycarbonylamino-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide (184709-80-6) + acetyl chloride (75-36-5) → 2-[2-(4-acetylaminophenyl)-5-benzyloxycarbonylamino-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)acetamide

Guidance literature:

With sodium carbonate; In tetrahydrofuran;

Reference yield:

2-[2-(4-aminophenyl)-5-benzyloxycarbonylamino-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide (184709-80-6) + isopropyl chloroformate (108-23-6) → 2-[5-benzyloxycarbonylamino-2-(4-isopropoxycarbonylaminophenyl)-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)acetamide

Guidance literature:

sodium carbonate; In tetrahydrofuran;

upstream raw materials:

iron

2-[5-benzyloxycarbonylamino-2-(4-nitrophenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide

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