4-methyl hydrogen D-aspartate hydrochloride

Base Information

• Chemical Name: 4-methyl hydrogen D-aspartate hydrochloride
• CAS No.: 22728-89-8
• Molecular Formula: C5H9NO4·ClH
• Molecular Weight: 183.592
• Hs Code.: 2922509090
• Mol file: 22728-89-8.mol

Synonyms:Asparticacid, 4-methyl ester, hydrochloride, D- (7CI,8CI);D-Aspartic acid, 4-methyl ester, hydrochloride (9CI);

Chemical Property of 4-methyl hydrogen D-aspartate hydrochloride

Chemical Property:

• Vapor Pressure: 3.6E-05mmHg at 25°C
• Boiling Point: 329 °C at 760 mmHg
• Flash Point: 152.8 °C
• PSA: 100.62000
• LogP: 0.88840
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

D-AsparticAcid4-MethylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-methyl hydrogen D-aspartate hydrochloride

There total 3 articles about 4-methyl hydrogen D-aspartate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + (2R)-aspartic acid (1783-96-6,25608-40-6,27881-03-4,32505-46-7,52526-39-3) → D-2-amino-3-methoxycarbonylpropionic acid hydrochloride (22728-89-8)

Guidance literature:

With thionyl chloride; at -30 - 10 ℃;

DOI:10.1039/a702410j

Reference yield:

(2R)-aspartic acid (1783-96-6,25608-40-6,27881-03-4,32505-46-7,52526-39-3) → D-2-amino-3-methoxycarbonylpropionic acid hydrochloride (22728-89-8)

Guidance literature:

With thionyl chloride; In methanol;

Reference yield:

methanol (67-56-1) + L-Aspartic acid (56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) → D-2-amino-3-methoxycarbonylpropionic acid hydrochloride (22728-89-8)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; for 2h;

upstream raw materials:

methanol

(2R)-aspartic acid

L-Aspartic acid

Downstream raw materials:

(+)-N-Cbz-β-methyl-D-aspartate

L-asparic acid C₁-t-butyl C₄-methyl diester hydrochloride

(2R)-2-[(tert-butoxycarbonyl)amino]-4-methoxy-4-oxobutanoic acid

D-2-amino-3-methylaminopropionic acid