1-Butyl-3-ethylurea

Base Information

• Chemical Name: 1-Butyl-3-ethylurea
• CAS No.: 10310-60-8
• Molecular Formula: C₇H₁₆N₂O
• Molecular Weight: 144.217
• NSC Number: 28774
• DSSTox Substance ID: DTXSID40145646
• Wikidata: Q83010208
• Mol file: 10310-60-8.mol

Synonyms:1-Butyl-3-ethylurea;10310-60-8;Urea, 1-butyl-3-ethyl-;Urea, N-butyl-N'-ethyl-;N-butyl-N'-ethylurea;NSC 28774;BRN 1751943;NSC28774;3-butyl-1-ethylurea;3-04-00-00299 (Beilstein Handbook Reference);SCHEMBL969649;DTXSID40145646;NSC-28774;AKOS006222998

Chemical Property of 1-Butyl-3-ethylurea

Chemical Property:

• Vapor Pressure: 0.0037mmHg at 25°C
• Boiling Point: 280.8°Cat760mmHg
• Flash Point: 122.3°C
• Density: 0.907g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 144.126263138
• Heavy Atom Count: 10
• Complexity: 93.6

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCNC(=O)NCC

Technology Process of 1-Butyl-3-ethylurea

There total 11 articles about 1-Butyl-3-ethylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.6%

C9H10N4O (1197158-28-3) + N-butylamine (109-73-9,85404-21-3) → N-Butyl-N'-ethylurea (10310-60-8)

Guidance literature:

In toluene; at 70 - 80 ℃; for 1h;

DOI:10.1055/s-0029-1217820

Reference yield: 80.0%

diethyl sulfate (64-67-5) + 1-butyl-urea (592-31-4) → N-Butyl-N'-ethylurea (10310-60-8)

Guidance literature:

With potassium hydroxide; potassium carbonate; tetrabutyl-ammonium chloride; In toluene; for 2h; Heating;

DOI:10.1007/BF00816855

Reference yield: 80.0%

diethyl sulfate (64-67-5) → N-Butyl-N'-ethylurea (10310-60-8)

Guidance literature:

upstream raw materials:

N-butylamine

ethyl isocyanate

1-bromo-butane

N-Ethylurea