2-Amino-1-benzothiophene-3-carboxylic acid

Base Information

Chemical Name:2-Amino-1-benzothiophene-3-carboxylic acid
CAS No.:18774-50-0
Molecular Formula:C9H7NO2S
Molecular Weight:193.22200
Hs Code.:
European Community (EC) Number:873-438-0
DSSTox Substance ID:DTXSID60591666
Wikidata:Q82485498
Mol file:18774-50-0.mol

Synonyms:18774-50-0;2-amino-1-benzothiophene-3-carboxylic acid;Benzo[b]thiophene-3-carboxylic acid, 2-amino-;2-aminobenzo[b]thiophene-3-carboxylic acid;SCHEMBL2206020;DTXSID60591666;KFVFYVHYWICGOY-UHFFFAOYSA-N;DB-292575;EN300-143486

Suppliers and Price of 2-Amino-1-benzothiophene-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Amino-1-benzothiophene-3-carboxylic acid

Chemical Property:

PSA：91.56000
LogP:2.76290
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:193.01974964
Heavy Atom Count:13
Complexity:222

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(S2)N)C(=O)O

Technology Process of 2-Amino-1-benzothiophene-3-carboxylic acid

There total 2 articles about 2-Amino-1-benzothiophene-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 7311-95-7
ethyl 2-amino-1-benzothiophene-3-carboxylate

: 18774-50-0
2-amino-1-benzothiophene-3-carboxylic acid

Guidance literature:: ethyl 2-amino-1-benzothiophene-3-carboxylate; With sodium hydroxide; In tetrahydrofuran; ethanol; water; for 8h; Reflux;

With hydrogenchloride; In water; pH=5;
DOI:10.1016/j.bmc.2011.01.041

Reference yield:

: 18774-50-0
2-amino-1-benzothiophene-3-carboxylic acid

Guidance literature:: With -alkaline sodium hypobromite solution; at 80 - 90 ℃;

Reference yield: 21.0%

: 18774-50-0
2-amino-1-benzothiophene-3-carboxylic acid

: N-Boc-trans-1,4-bis(aminomethyl)cyclohexane

: tert-butyl {[trans-4-({[(2-amino-1-benzothiophen-3-yl)carbonyl]amino}methyl)cyclohexyl]methyl}carbamate

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methyl-THF; water;